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Animal Model

Animal Model

Animal models play a crucial role in scientific research and are widely used to study various aspects of biology, medicine, and behavior. These models involve the use of animals, such as mice, rats, rabbits, and primates, to mimic human physiology and understand disease mechanisms, develop new treatments, and test the safety and efficacy of drugs. Animal models provide a controlled experimental environment that allows researchers to investigate complex biological processes in a living system. By selectively breeding animals or using genetic modification techniques, scientists can create models that exhibit specific traits or conditions relevant to human diseases. For instance, mice with a specific gene mutation can be used to study the genetic basis of cancer or neurodegenerative disorders.

1643 Result Found
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  • Prf1-KO

    Prf1-KO

    • KI/KO Gene : Prf1
    • Nomenclature : C57BL/6JSmoc-Pr
    • Exon : Exon 3
    • Description : Model Descripti
    • Synonyms : perforin Pfn Pf
  • Pten-KO

    Pten-KO

    • KI/KO Gene : Pten
    • Nomenclature : C57BL/6JSmoc-Pt
    • Exon : Exon 5
    • Description : Model Descripti
    • Disease : Autism Spectrum
  • Pten-Flox

    Pten-Flox

    • KI/KO Gene : Pten
    • Nomenclature : C57BL/6JSmoc-Pt
    • Exon : Exon s
    • Description : Model Descripti
    • Synonyms : 2310035O07Rik A
  • R26-CAG-LSL-hFGFR2-IRES-Luc-2A-EGFP

    • KI/KO Gene : Gt(ROSA)26Sor
    • Nomenclature : C57BL/6JSmoc-Gt
    • Description : Model Descripti
    • Synonyms : R26,ROSA26,AV25
    • Application : Cancer
  • R26-CAG-LSL-hIDH1*R132H-IRES-Luc-2A-tdTomato

    • KI/KO Gene : Gt(ROSA)26Sor
    • Nomenclature : C57BL/6JSmoc-Gt
    • Description : Model Descripti
    • Synonyms : R26,ROSA26,AV25
    • Reference : MGI:5582197
  • R26-CAG-LSL-hFGFR3-IRES-Luc-2A-EGFP

    • KI/KO Gene : Gt(ROSA)26Sor
    • Nomenclature : C57BL/6JSmoc-Gt
    • Description : Model Descripti
    • Synonyms : R26,ROSA26,AV25
    • Application : Cancer Research
  • R26-CAG-LSL-hFGFR3*S249C-IRES-Luc-2A-EGFP

    • KI/KO Gene : Gt(ROSA)26Sor
    • Nomenclature : C57BL/6JSmoc-Gt
    • Description : Model Descripti
    • Synonyms : R26,ROSA26,AV25
    • Application : Cancer Research
  • R26-hCD46-IRES-tdTomato

    R26-hCD46-IRES-tdTomato

    • KI/KO Gene : Gt(ROSA)26Sor
    • Nomenclature : C57BL/6JSmoc-Gt
    • Description : Model Descripti
    • Synonyms : R26,ROSA26,AV25
    • Application : Immune-Related
  • R26-CAG-LSL-hTARDBP*A315T-EGFP

    • KI/KO Gene : Gt(ROSA)26Sor
    • Nomenclature : C57BL/6JSmoc-Gt
    • Description : Model Descripti
    • Synonyms : R26,ROSA26,AV25
    • Application : Amyotrophic Lat
  • R26-CAG-LSL-hSOD1*G94A-IRES-EGFP

    • KI/KO Gene : Gt(ROSA)26Sor
    • Nomenclature : C57BL/6JSmoc-Gt
    • Description : Model Descripti
    • Disease : Amyotrophic Lat
    • Synonyms : R26,ROSA26,AV25
  • Slc6a3-KO

    Slc6a3-KO

    • KI/KO Gene : Slc6a3
    • Nomenclature : C57BL/6JSmoc-Sl
    • Exon : Exon 4
    • Description : Model Descripti
    • Disease : schizophrenia
  • Slc6a1-KO(3)

    Slc6a1-KO(3)

    • KI/KO Gene : Slc6a1
    • Nomenclature : C57BL/6JSmoc-Sl
    • Exon : Exon 7.
    • Description : Model Descripti
    • Disease : schizophrenia
  • Slc34a1-KO

    Slc34a1-KO

    • KI/KO Gene : Slc34a1
    • Nomenclature : C57BL/6JSmoc-Sl
    • Exon : Exon 3-6
    • Description : Model Descripti
    • Disease : Hereditary Hypo
  • Srf-Flox

    Srf-Flox

    • KI/KO Gene : Srf
    • Nomenclature : C57BL/6JSmoc-Sr
    • Exon : Exon s
    • Description : Model Descripti
    • Disease : Dilated Cardiom
  • Snrpn-KO

    Snrpn-KO

    • KI/KO Gene : Snrpn
    • Nomenclature : C57BL/6JSmoc-Sn
    • Exon : Exon 6
    • Description : Model Descripti
    • Disease : Prader-Willi Sy
  • Stat3-Flox(2)

    Stat3-Flox(2)

    • KI/KO Gene : Stat3
    • Nomenclature : C57BL/6JSmoc-St
    • Exon : Exon 18-20
    • Description : Model Descripti
    • Disease : inflammatory bo
  • Trp53-flox-R172H

    Trp53-flox-R172H

    • KI/KO Gene : Trp53
    • Nomenclature : C57BL/6JSmoc-Tr
    • Description : Model Descripti
    • Synonyms : bbl; bfy; bhy;
    • Reference : MGI:3818748
  • Tyro3-KO

    Tyro3-KO

    • KI/KO Gene : Tyro3
    • Nomenclature : C57BL/6JSmoc-Ty
    • Exon : Exon 3
    • Description : Model Descripti
    • Disease : Autoimmune Dise
  • Abcg2-KO(SD)

    Abcg2-KO(SD)

    • KI/KO Gene : Abcg2
    • Nomenclature : SD-Abcg2em1Smoc
    • Exon : Exon 4-5
    • Description : Model Descripti
    • Strain : Repository Live
  • Cd200-KO(LEW)

    Cd200-KO(LEW)

    • KI/KO Gene : Cd200
    • Nomenclature : LEW-Cd200em1Smo
    • Exon : Exon 2-5
    • Description : Model Descripti
    • Strain : Developing
  • Bdnf-Flox(SD)

    Bdnf-Flox(SD)

    • KI/KO Gene : Bdnf
    • Nomenclature : SD-Bdnfem1(flox
    • Exon : Exon 2
    • Description : Model Descripti
    • Strain : Developing
  • Bbc3-KO(SD)

    Bbc3-KO(SD)

    • KI/KO Gene : Bbc3
    • Nomenclature : SD-Bbc3em1Smoc
    • Exon : Exon 2-4
    • Description : Model Descripti
    • Strain : Developing
  • hAPP mutation(SD)

    hAPP mutation(SD)

    • KI/KO Gene : App
    • Nomenclature : SD-Apptm1(hAPP
    • Description : Model Descripti
    • Strain : Developing
    • Synonyms : Abeta
  • hAPOE2(SD)

    hAPOE2(SD)

    • KI/KO Gene : Apoe
    • Nomenclature : SD-Apoeem1(hAPO
    • Description : Model Descripti
    • Strain : Repository Live
    • Synonyms : apo-E
  • Grm5-KO(SD)

    Grm5-KO(SD)

    • KI/KO Gene : Grm5
    • Nomenclature : SD-Grm5em1Smoc
    • Exon : Exon 2
    • Description : Model Descripti
    • Strain : Repository Live