| Field | Specification |
|---|---|
| Activity | |
| Cas No. | |
| Molecular Weight | |
| Product Type | |
| Signaling Pathway | |
| SMILES | |
| Target |
Compound Overview
(E/Z)-AG490 (CAS 134036-52-5) is a research-grade small molecule supplied by TargetMol.
Physical Properties
| CAS Number | 134036-52-5 |
|---|---|
| Molecular Formula | C17H14N2O3 |
| Molecular Weight | 294.30 g/mol |
| SMILES | C(=C(C(NCC1=CC=CC=C1)=O)CN)C2=CC(O)=C(O)C=C2 |
| Form | Solid |
| Shipping | Room Temperature (RT) |
Biological Activity
(E/Z)-AG490 ((E/Z)-Tyrphostin AG490) is a racemic compound of isomers (E)-AG490 and (Z)-AG490. (E)-AG490 is an inhibitor of tyrosine kinase that inhibits EGFR, Stat-3 and JAK2/3.
Safety & Regulatory
For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.
Yes, our inhibitors can be used for animal/in vivo experiments. However, some compounds may not have literature supporting their use in animal experiments. In such cases, we cannot guarantee efficacy.
There are various standards for defining the purity, and we do not have fixed purity standard. The purity of most products are above 98% and can be used for control experiments, including cell experiments, animal experiments, general laboratory experiments, and high-throughput screening. Our product purity also meets the industrial standard.
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close
equivalents, or discuss custom synthesis with the right QC documentation (RUO).
Research budgets are tight — we get it. That's why we've put together a fresh round of exclusive promotions designed to help you stock up on the reagents, kits, and consumables your lab depends on, without stretching your budget.
🔬 What's on offer right now:
10% Off Pre-Designed siRNA Sets — use code SIRNA10
20% Off Transmembrane Proteins — use code TM20
$50 Off All ELISA Kits — auto-applied at checkout (code ELISA50)
50% Off Lab Consumables + Free Shipping on orders $500+
15% Off Proteins from Trusted Suppliers — use code PROTEIN15
$99 Pipette Filler Promotion Package (reg. $236)
Save 10% on your first order of any R&D grade DENARASE® with code DENARASE10 at checkout.
