Custom siRNA Synthesis

High-quality siRNA duplexes for gene silencing. HPLC purification, ISO-certified, with guaranteed performance. Starting from $59.

About Custom siRNA Synthesis

Small interfering RNA (siRNA) is a double-stranded RNA of 20 to 25 nucleotides that participates in RNA interference (RNAi) to silence target genes.

RNAi technology can specifically eliminate or turn off the expression of target genes, and it has been widely used in gene function research, infectious disease treatment, and cancer therapy. Biohippo partners with experienced oligonucleotide production teams to provide siRNA design and custom synthesis services, including standard siRNA oligos and modified siRNA oligos, to meet your specific research needs.

siRNA Synthesis Service Specifications

Product Name Size Purification Turnaround Time Price
Standard siRNA nmol - μmol HPLC 4-20 days From $59
Modified siRNA nmol - μmol HPLC 5-25 days Get Quote

Control siRNA Options

Essential controls for validating your RNAi experiments

Product Name Size Purification Availability Price
NC siRNA (Negative Control) 3 nmol HPLC In Stock Get Quote
NC FAM siRNA (Labeled Control) 3 nmol HPLC In Stock Get Quote
GAPDH Positive Control siRNA 3 nmol HPLC In Stock Get Quote
P53 Positive Control siRNA 3 nmol HPLC In Stock Get Quote
Beta-actin Positive Control siRNA 3 nmol HPLC In Stock Get Quote

siRNA Guaranteed Package

Complete packages with guaranteed knockdown efficiency

Modified siRNA Package

Target gene modified siRNA 4 pairs (4×12nmol)
NC modified siRNA 1 pair (1×3nmol)
NC FAM modified siRNA 1 pair (1×3nmol)
Positive control siRNA 1 pair (1×3nmol)
7+
Days
HPLC
Purified

Enhanced stability & efficiency

Get Quote

Our Service Workflow

From sequence design to delivery, we ensure quality at every step

1

Design

siRNA sequence design and optimization for your target gene

2

Synthesis

High-efficiency chemical synthesis with real-time monitoring

3

Purification

HPLC purification to remove short fragments

4

QC & Delivery

Mass spec verification and complete COA provided

Why Our siRNA Service Stands Out

>99% Purity

HPLC purification removes short fragments and ensures high-quality products

Flexible Scale

From nmol to μmol scale to meet various research needs

Optimal Length

20-25 nucleotides for effective RNA interference

Rich Modifications

FAM, cholesterol, phosphorothioate, and more options available

Fast Turnaround

4-20 days delivery depending on complexity

Quality Guarantee

Complete QC report with mass spec and HPLC data

Request a Quote

Fill out the form below for custom siRNA synthesis pricing and delivery timeline

Hours

Mon-Fri 9AM-6PM EST

We'll get back to you within 24 business hours. Prefer email? Send to orders@biohippo.com

Request Submitted Successfully

Thank you for your inquiry. Our team will contact you within 24 hours.

Ready to start an project?

Share your application, any details of your project, or special requirements. Our team will contact you after receiving your request.