| Field | Specification |
|---|---|
| Target | |
| Alternative names | Cd14Monocyte differentiation antigen CD14 ELISA Kit; Myeloid cell-specific leucine-rich glycoprotein ELISA Kit; CD antigen CD14 ELISA Kit |
| UniProt # | |
| Species | |
| Reactivity | |
| Applications | |
| Assay type | |
| Sample type(s) | serum, plasma, tissue homogenates |
| Sensitivity | |
| Detection range | |
| Detection wavelength | |
| Assay time | |
| Catalog no. (Mfr.) | |
| Main SKU |
Background
soluble cluster of differentiation 14 (CD14) is a biological molecule commonly studied in immunology research. It is commonly used as a molecular readout in mechanistic and biomarker-focused studies.
UniProt: Q63691
Biological context
Researchers often monitor soluble cluster of differentiation 14 in serum, plasma, and tissue homogenates to better understand themes such as innate and adaptive immune responses, cytokine signaling networks, and host–pathogen interactions. In many model systems, measured levels can shift with physiology, experimental perturbation, or disease-associated changes, making careful biological interpretation important.
Interpreting changes in measured levels
Depending on sample matrix and study design, increases or decreases in soluble cluster of differentiation 14 may reflect differences in expression, secretion, turnover, or compartmentalization rather than a single mechanism. Interpretation is typically strengthened by evaluating related molecules (for example, cytokines, chemokines, acute-phase proteins, and immune-cell activation markers) and by keeping pre-analytical variables consistent across groups.
Nomenclature
In publications and databases, soluble cluster of differentiation 14 may also appear under names such as Cd14Monocyte differentiation antigen CD14 and Myeloid cell-specific leucine-rich glycoprotein. When comparing studies, confirm that the reported analyte refers to the same molecule and species context.
Why ELISA data are widely used
ELISA is a common approach for quantitative measurement of proteins and biomarkers in complex samples, enabling comparisons across experimental groups and time points. When integrating results with other readouts, consider species biology, sample type, and the broader pathway context that soluble cluster of differentiation 14 participates in.
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Exploring the Mechanism on the Medullary Visceral Zone Inhibiting the Cholinergic Anti-inflammatory Pathway Induced by Sepsis
HB Li,Mediators of Inflammation,2020
