GTF2IRD1 Antibody, Biotin conjugated

Overview

This polyclonal anti-GTF2IRD1 antibody raised in Rabbit, conjugated with Biotin, tested in ELISA. Designed to detect GTF2IRD1 in Human for epigenetics and nuclear signaling research.

Key elements and design rationale

• Immunogen: Recombinant Human General transcription factor II-I repeat domain-containing protein 1 protein (436-560AA) — determines epitope; confirm sample prep compatibility.
• Host (Rabbit): Requires anti-rabbit-IgG secondary matching isotype IgG.
• Polyclonal: Multiple epitopes = robust signal; lot-to-lot variability — include controls.
• Isotype (IgG): Match secondary, Protein A/G, and isotype controls to IgG.
• Purification (Protein G purification): Enriches Ig classes; reduces non-specific background.
• Biotin: Streptavidin/avidin amplification; block endogenous biotin in biotin-rich samples.

Biological background

GTF2IRD1 (also: CREAM1, General transcription factor II I repeat domain containing protein 1, General transcription factor II-I repeat domain-containing protein 1, General transcription factor III, GT2D1_HUMAN, GTF2I repeat domain containing protein 1, GTF2I repeat domain-containing protein 1, GTF2IRD1, GTF3, Muscle TFII I repeat domain-containing protein 1, Muscle TFII-I repeat domain-containing protein 1, MUSTRD1, MusTRD1/BEN, RBAP2, Slow muscle fiber enhancer binding protein, Slow-muscle-fiber enhancer-binding protein, USE B1 binding protein, USE B1-binding protein, WBSCR11, WBSCR12, Williams Beuren syndrome chromosome region 11 protein, Williams-Beuren syndrome chromosomal region 11 protein, Williams-Beuren syndrome chromosomal region 12 protein) — studied in Human systems. Expression, localization, and PTMs vary across cell types and disease states. Consult UniProt, NCBI Gene, and primary literature for current GTF2IRD1 annotation relevant to epigenetics and nuclear signaling.

Common research applications

• ELISA: Quantify soluble target; ensure samples within the linear detection range.

Notes for experimental interpretation

• Isotype controls: IgG from Rabbit at equivalent concentration.
• Cross-reactivity: Polyclonal: validate with KO/KD controls.
• Matrix effects: Verify dilution linearity in your sample matrix.
• Reactivity: Confirmed for Human; extrapolation requires validation.

This product is a polyclonal antibody purified from rabbit antiserum.

• Datasheet (12781523)

Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.