DENARASE® Endonuclease — Product Overview
Serratia marcescens-derived endonuclease | ≥98% purity | Active on all nucleic acid forms
- Purity ≥98% (SDS-PAGE verified)
- Activity >250 U/µl
- Wild-type: physiological salt conditions
- High Salt: active at >150 mM — broadens process flexibility
- Gram-positive Bacillus sp. host — low endotoxin risk
- Technically equivalent to GMP grade — seamless scale-up
- Purity ≥98% | Activity >250 U/µl
- Manufactured under EU GMP regulations
- No animal-origin raw materials, no antibiotics, no Triton X-100
- No TSE/BSE risk materials
- Suitable for biopharmaceutical commercial manufacturing
- Change Guidance Documents available for regulatory submissions
Scientific specifications sourced from c-LEcta GmbH. DENARASE® specifically hydrolyzes phosphodiester bonds, producing fragments of ~3–5 base pairs. Active on all nucleic acid forms (ss, ds, linear, circular, supercoiled DNA and RNA). Production host: gram-positive Bacillus sp. — no TSE/BSE risk materials, Triton X-100, or animal-origin inputs. R&D-grade produced under ISO 9001; GMP-grade complies with EU GMP regulations. 10% discount (code DENARASE10) applies to one order of R&D grade products only — GMP grade is excluded.Not for therapeutic or clinical use.