SCN10A Antibody, FITC conjugated

Overview

This polyclonal anti-SCN10A antibody raised in Rabbit, conjugated with FITC. Designed to detect SCN10A in Human for neuroscience research.

Key elements and design rationale

• Immunogen: Recombinant Human Sodium channel protein type 10 subunit alpha protein (992-1099AA) — determines epitope; confirm sample prep compatibility.
• Host (Rabbit): Requires anti-rabbit-IgG secondary matching isotype IgG.
• Polyclonal: Multiple epitopes = robust signal; lot-to-lot variability — include controls.
• Isotype (IgG): Match secondary, Protein A/G, and isotype controls to IgG.
• Purification (Protein G purification): Enriches Ig classes; reduces non-specific background.
• FITC: Direct fluorescence (Ex490/Em525); protect from light; use antifade.

Biological background

SCN10A (also: hPN3, mPN3, Peripheral nerve sodium channel 3, Pn3 (gene name), PN3, SCN10A, SCNAA_HUMAN, Sensory neuron sodium channel, Sns (gene name), SNS, Sodium channel protein type 10 subunit alpha, Sodium channel protein type X alpha subunit, Sodium channel protein type X subunit alpha, Voltage-gated sodium channel alpha subunit Nav1.8, Voltage-gated sodium channel subunit alpha Nav1.8) — studied in Human systems. Expression, localization, and PTMs vary across cell types and disease states. Consult UniProt, NCBI Gene, and primary literature for current SCN10A annotation relevant to neuroscience.

Common research applications

• Refer to product documentation for confirmed application data.

Notes for experimental interpretation

• Isotype controls: IgG from Rabbit at equivalent concentration.
• Cross-reactivity: Polyclonal: validate with KO/KD controls.
• Matrix effects: Verify dilution linearity in your sample matrix.
• Reactivity: Confirmed for Human; extrapolation requires validation.

This product is a polyclonal antibody purified from rabbit antiserum.

• Datasheet (12783637)

Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.