Therapeutic Drug Monitoring

Research-use assays that quantify circulating levels of therapeutic drugs — infliximab, adalimumab, ustekinumab, vedolizumab and more — so you can relate drug exposure to response.

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Image ProductProduct Type ApplicationPrice Status ACTION
Infliximab ELISA Kit
Target: Infliximab
ELISA Kits, PK ELISA Kits ELISA
$1,226.00
Regular price $1,226.00
In Stock at Manufacturer
Anti-Infliximab Polyclonal Antibody
Target: Infliximab
Antibodies, Primary Antibodies ELISA
From $452.00
Regular price From $452.00
In Stock at Manufacturer
Anti-Infliximab ELISA Kit
Target: Infliximab
ELISA Kits, ADA ELISA Kits ELISA
$1,498.00
Regular price $1,498.00
In Stock at Manufacturer
Infliximab ELISA Kit
Target: Infliximab
ELISA Kits ELISA
$520.00
Regular price $520.00
In Stock at Manufacturer
Human Infliximab ELISA Kit
Target: Infliximab
ELISA Kits ELISA
From $416.00
Regular price From $416.00
In Stock at Manufacturer

About Therapeutic Drug Monitoring

Therapeutic drug monitoring (TDM) reagents quantify the circulating concentration of a dosed drug — most often a biologic such as a TNF-α inhibitor — so researchers can relate exposure to response and keep levels inside the therapeutic window. This collection gathers research-use ELISA kits, biosimilar reference standards, and detection antibodies for measuring drug trough and free-drug levels of infliximab, adalimumab, ustekinumab, vedolizumab, and related therapeutics.

Choosing a drug-exposure assay: TDM vs Pharmacokinetics vs Immunogenicity

Three neighbouring assay families answer three different questions about a therapeutic. TDM is the format in this collection; the table shows when to reach for it versus its two siblings.

Dimension Therapeutic Drug Monitoring Pharmacokinetics (PK) Drug Immunogenicity (ADA/NAb)
What it measuresConcentration of the drug in a sampleConcentration of the drug over timeAntibodies the host raises against the drug
AnalyteFree / total drugFree / total drugAnti-drug antibody (ADA); neutralizing antibody (NAb)
Question answeredIs exposure inside the therapeutic window right now?How is the drug absorbed, distributed, and cleared?Is the host mounting an immune response that lowers exposure or efficacy?
Typical readoutTrough / free-drug level (µg/mL)Cmax, AUC, t½, clearanceADA titer; % neutralization
Usual stageDose management & exposure–response studiesPreclinical / early clinical characterizationSafety & loss-of-response investigation
Watch-outsADA in the sample can interfere with free-drug readingNeeds a time course, not a single pointDrug in the sample can mask ADA (drug tolerance)

How to read this: TDM and PK both quantify the drug — the difference is intent. Use TDM when the goal is to check a level against a target window; use Pharmacokinetics when you need the full exposure profile over time. When exposure is unexpectedly low or a response fades, switch to Drug Immunogenicity to test for anti-drug antibodies — the three are complementary, and a complete study often runs all three on the same samples.

Recommended TDM kits

Human Infliximab ELISA Kit

View kit →

Human Adalimumab ELISA Kit

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Human Ustekinumab ELISA Kit

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Infliximab (Remicade) Pharmacokinetic ELISA

View kit →

Related reading

Trough-level monitoring of anti-TNF biologics
Free vs total drug assays: what the format changes
When loss of response means anti-drug antibodies

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