5-Ethynyl-2’-deoxyuridine

5-Ethynyl-2’-deoxyuridine (EdU) is a thymidine analog used to label newly synthesized DNA, enabling precise detection of cell proliferation via click chemistry. Unlike traditional methods such as BrdU incorporation, EdU does not require DNA denaturation, preserving cellular integrity and improving detection sensitivity. In neuroscience, EdU is extensively used to monitor neurogenesis, particularly in studies of brain development, injury response, and neurodegenerative disease models. Its compatibility with multiplexed imaging makes it a powerful tool for tracking neural stem cell dynamics and evaluating regenerative therapies.

Classification: Caution: Substance not yet fully tested.

Safety Phrases:

• S22 - Do not breathe dust
• S24/25 - Avoid contact with skin and eyes
• S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection

5-Ethynyl-2’-deoxyuridine (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-597)

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

• Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
• Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
• Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
• QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
• Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

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