Ebselen

SKU:BHB11900033
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    Overview
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    Ebselen is a research-grade small-molecule inhibitor of Glutathione peroxidase mimic for Cancer and Apoptosis studies. Supplied as a off-white solid with >99% purity (CAS 60940-34-3, MW 274.18) soluble in DMSO and 100% ethanol; store at -20°C. For research use only.
    Cas No. 60940-34-3
    Molecular Formula C13H9NOSe
    Purity >99%
    Application Notes Glutathione peroxidase mimic
    Available Options

    Select the variant that best fits your experiment. Availability and lead time may vary by option.

    • Options: Size (2) — 10 mg, 50 mg.
    • Lead time: options listed as “in stock at manufacturer” typically ship in 2-3 business days; other statuses may take longer.
    • Storage: -20ºC
    • Shipping: ships at ambient temperature.
    • Upon receipt: store at the recommended temperature as soon as possible.
    • Sales terms and conditions: Please review prior to ordering.
    Options selector
    Catalog no. Size
    SIH-204-10MG 10 mg
    SIH-204-50MG 50 mg
    Field Specification
    Activity
    • Inhibitor
    Alternative Names 2-Phenyl-1,2-benzoselenazol-3(2H)-one
    Cas No. 60940-34-3
    Form Off-white Solid
    Molecular Weight 274.18
    Product Type
    • Biochemicals
    • Small Molecules
    Purity >99%
    Shipping Shipped Ambient
    SMILES C1=CC=C(C=C1)N2C(=O)C3=CC=CC=C3[Se]2
    Solubility Soluble in DMSO and 100% ethanol
    Source Synthetic
    Storage -20ºC

    Ebselen is a selenium-containing compound that mimics glutathione peroxidase activity and scavenges reactive oxygen and nitrogen species. It has been explored as a neuroprotective agent in conditions such as stroke, tinnitus, and bipolar disorder. Ebselen reduces oxidative stress by neutralizing hydrogen peroxide and lipid hydroperoxides, thereby protecting neurons from oxidative damage. Its antioxidant and anti-inflammatory properties make it a promising candidate for mitigating neuronal injury in neurodegenerative diseases.

    Classification: Harmful: May be harmful if inhaled, swallowed or absorbed through skin.

    Safety Phrases:

    • S22 - Do not breathe dust
    • S24/25 - Avoid contact with skin and eyes
    • S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection

    Risk Phrases:

    23/25-33-50/53

    Hazard Phrases:

    H301-H331-H373-H410

    Precautionary Phrases:

    P261-P273-P301 + P310-P311-P501

    Ebselen (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-204)

    Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

    • Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
    • Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
    • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
    • QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
    • Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

    To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

    Can’t find the compound you’re looking for?
    Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).

    1. Schewe T. (1995) Gen Pharmacol. 26(6): 1153-1169.
    2. Parnham M., Seis H. (2000) Expert Opin Investig Drugs. 9(3): 607-619.
    3. Yamaguchi T., et al. (1998) Stroke. 29(1): 12-17.
    4. Kil J., Pierce C., Tran H., Gu R., Lynch E.D. (2007) Hearing Research. 226(1-2): 44-51.

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