Niclosamide

Niclosamide is an anthelmintic drug that has gained attention for its ability to modulate multiple signaling pathways, including Wnt/β-catenin, mTOR, and NF-κB. In neuroscience, niclosamide is investigated for its neuroprotective and anti-inflammatory properties. It has shown efficacy in reducing neuroinflammation and oxidative stress in models of neurodegenerative diseases. By targeting key regulatory pathways, niclosamide offers insights into the molecular mechanisms of neuronal survival and immune modulation. Its repurposing potential makes it a promising candidate for therapeutic development in neurodegeneration.

Classification: Not WHMIS controlled.

Safety Phrases:

• S22 - Do not breathe dust.
• S24/25 - Avoid contact with skin and eyes.
• S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.

Niclosamide (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-406)

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

• Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
• Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
• Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
• QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
• Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).