Nifedipine

Nifedipine is a dihydropyridine calcium channel blocker primarily used to treat hypertension and angina. In neuroscience, it has been employed to investigate the role of L-type calcium channels in neuronal function and neurovascular regulation. Nifedipine’s ability to modulate calcium influx has implications for neuroprotection, particularly in ischemic injury and neurodegenerative conditions where calcium overload contributes to cell death. Its use in experimental models helps elucidate calcium-dependent signaling pathways in neurons and glial cells.

Classification: Toxic. May be harmful or fatal if inhaled, swallowed or absorbed through skin.

Safety Phrases:

• S22 - Do not breathe dust
• S24/25 - Avoid contact with skin and eyes
• S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection

Risk Phrases:

• R20/21/22- Harmful by inhalation, in contact with skin and if swallowed
• R60 - May impair fertility
• R61 - May cause harm to the unborn child

Hazard Phrases:

H302

Nifedipine (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-309)

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

• Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
• Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
• Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
• QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
• Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).