Retinoic acid

Retinoic acid, a metabolite of vitamin A, plays a critical role in neural development and differentiation. It regulates gene expression by activating nuclear retinoic acid receptors (RARs), which influence neuronal patterning, synaptic plasticity, and neurogenesis. In neurodegenerative disease research, retinoic acid has been studied for its ability to promote neuronal survival and regeneration. It is also involved in modulating inflammatory responses and oxidative stress, making it a candidate for therapeutic intervention in conditions such as Alzheimer's and Parkinson's disease.

Classification: Toxic. May be harmful or fatal is inhaled, swallowed or absorbed through skin.

Safety Phrases:

• S22 - Do not breathe dust
• S24/25 - Avoid contact with skin and eyes
• S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection

Risk Phrases:

• R20/21/22 - Harmful by inhilation, in contact with skin and if swallowed
• R40 - Limited evidence of a carcinogenic effect
• R46 - May cause heritable genetic damage
• R62 - Possible risk of impaired fertility

Hazard Phrases:

H302-H411

Precautionary Phrases:

P273

Retinoic acid (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-258)

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

• Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
• Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
• Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
• QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
• Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).