| Field | Specification |
|---|---|
| Alternative names | Galantamine hydrobromide, Galantamine HBr, Galanthamine hydrobromide, Galanthamine, Galanthamine hydrogen bromide, SPECTRUM1501202, 1,2,3,4,6,7,7a,11c-Octahydro-9-methoxy-2-methyl-benzofuro(4,3,2-efg)(2)benzazocin-6-ol HBr, LS-185021, Galanthamine, Nivalin, Reminyl, Jilkon hydrobromide, Lycoremine hydrobromide |
| CAS no. | |
| Applications | |
| Source | Synthetic |
| Molecular weight | |
| Molecular formula | C17H22BrNO3 |
| Purity | |
| Bioactivity | Inhibitor |
| Activity | |
| Solubility | Soluble in water (12 mg/ml) or in DMSO (10 mg/ml) |
| SMILES | |
| InChIKey | |
| Form | White powder |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Galanthamine hydrobromide is a long-acting acetylcholinesterase inhibitor and an allosteric potentiator of nicotinic acetylcholine receptors. It is widely used in the treatment of Alzheimer’s disease due to its ability to enhance cholinergic neurotransmission. Galanthamine also exhibits neuroprotective effects by preventing β-amyloid-induced apoptosis and reducing amyloid precursor protein deposition. Its dual mechanism of action makes it a valuable compound in neurodegenerative disease research and cognitive enhancement studies.
Classification: D1B Toxic Material Causing Immediate and Serious Toxic Effects - Toxic by ingestion
Hazard statement(s):
H301 Toxic if swallowed.
Precautionary statement(s):
P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/ physician.
Galantamine Hydrobromide (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-530)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
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2. M Samochocki et al. J. Pharmacol. Exp. Ther. 2003 305:1024
3. E Arias et al. Neuropharmacology 2004 46:103
4. K Rockwood et al. J. Neurol. Neurosurg. Psychiatry 2001 71:589
5. S Chen et al. Curr. Neuropharmacol. 2007 5:127
