| Field | Specification |
|---|---|
| Alternative Names | ADAMTS2;PCINP;PCPNI;A disintegrin and metalloproteinase with thrombospondin motifs 2;ADAM-TS 2;ADAM-TS2;ADAMTS-2;Procollagen I N-proteinase;PC I-NP;Procollagen I/II amino propeptide-processing enzyme;Procollagen N-endopeptidase;pNPI |
| Antigen | |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Conjugate | |
| Formulation | |
| Gene ID | |
| Host | |
| Immunogen | Synthesized peptide derived from ADAMTS-2 . at AA range: 1140-1220 |
| Isotype | |
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| Target |
Product Overview
U-Blot® ADAMTS-2 Rabbit Polyclonal Antibody is a rabbit polyclonal antibody from UcallM Biosciences Inc, raised against ADAMTS-2. It has been validated for Western Blot, ELISA and reacts with Human, Mouse.
Validated Applications
| Target | ADAMTS-2 |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse |
| Applications | Western Blot, ELISA |
| Purification | Affinity Purified |
| Specificity | ADAMTS-2 Polyclonal Antibody detects endogenous levels of ADAMTS-2 protein. |
| Molecular Weight | Observed: 100 kDa |
| UniProt / Swiss-Prot | O95450 (Human) | Q8C9W3 (Mouse) |
Recommended dilutions: WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
Immunogen / Antigen
Synthesized peptide derived from ADAMTS-2 . at AA range: 1140-1220
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse. Confirm suitability for untested species before use.
Scientific Background
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature procollagen N-proteinase. This proteinase excises the N-propeptide of the fibrillar procollagens types I-III and type V. Mutations in this gene cause Ehlers-Danlos syndrome type VIIC, a recessively inherited connective-tissue disorder. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically
Safety & Handling
This antibody is validated for Western Blot, ELISA. Recommended dilutions: WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
Confirmed reactivity: Human, Mouse. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
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