| Field | Specification |
|---|---|
| Alternative Names | Voltage-dependent calcium channel subunit alpha-2/delta-3;Voltage-gated calcium channel subunit alpha-2/delta-3;[Cleaved into: Voltage-dependent calcium channel subunit alpha-2-3;Voltage-dependent calcium channel subunit delta-3] |
| Antigen | |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Conjugate | |
| Formulation | |
| Gene ID | |
| Host | |
| Immunogen | Synthetic Peptide of CaVα2δ3 AA range: 500-580 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Product Overview
U-Blot® CaVα2δ3 Rabbit Polyclonal Antibody is a rabbit polyclonal antibody from UcallM Biosciences Inc, raised against CaVα2δ3. It has been validated for Western Blot and reacts with Human, Rat, Mouse.
Validated Applications
| Target | CaVα2δ3 |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Reactivity | Human, Rat, Mouse |
| Applications | Western Blot |
| Purification | Affinity Purified |
| Specificity | CaVα2δ3 protein(A210) detects endogenous levels of CaVα2δ3 |
| Molecular Weight | Observed: 120 kDa |
| UniProt / Swiss-Prot | Q8IZS8 (Human) | Q9Z1L5 (Mouse) | Q8CFG5 (Rat) |
Recommended dilutions: WB 1:1000-2000
Immunogen / Antigen
Synthetic Peptide of CaVα2δ3 AA range: 500-580
Reactivity Notes
Confirmed cross-reactivity: Human, Rat, Mouse. Confirm suitability for untested species before use.
Scientific Background
calcium voltage-gated channel auxiliary subunit alpha2delta 3(CACNA2D3) Homo sapiens This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
Safety & Handling
This antibody is validated for Western Blot. Recommended dilutions: WB 1:1000-2000
Confirmed reactivity: Human, Rat, Mouse. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
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