U-Blot® G3BP1 Rabbit Monoclonal Antibody

SKU:BHA21800859
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    Overview
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    Anti-G3BP1 antibody (Rabbit host, monoclonal, Unconjugated). Validated for Western Blot, Immunohistochemistry, Immunofluorescence, Immunoprecipitation with reactivity to Human, Mouse, Rat.
    Clonality Monoclonal
    Host Rabbit
    Reactivity Human, Mouse, Rat
    Conjugate Unconjugated
    Isotype IgG, Kappa
    Clone PT1039R
    Applications Western Blot, Immunohistochemistry, Immunofluorescence, Immunoprecipitation, ELISA
    Options selector
    Catalog no. Size
    WR4869-50 50 uL
    WR4869-100 100 uL
    Available Options

    Select the variant that best fits your experiment. Availability and lead time may vary by option.

    • Options: Size: 50 uL
    • Lead time: options listed in "Availability Content"; other statuses may take longer.
    • Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
    • Shipping: cold-chain shipment (typically with ice packs).
    • Upon receipt: store at recommended temperature as soon as possible.
    • Sales terms and conditions: Please review prior to ordering.
    Field Specification
    Alternative Names G3BP1;G3BP;Ras GTPase-activating protein-binding protein 1;G3BP-1;ATP-dependent DNA helicase VIII;hDH VIII;GAP SH3 domain-binding protein 1
    Antigen
    • Ras GTPase-activating protein-binding protein 1
    Cellular Localization Cytoplasm, cytosol . Perikaryon . Cytoplasm, Stress granule . Nucleus . Cytoplasmic in proliferating cells (PubMed:11604510). Cytosolic and partially nuclear in resting cells (PubMed:11604510). Recruited to stress granules in response to arsenite treatment (PubMed:12642610, PubMed:20180778). The unphosphorylated form is recruited to stress granules (PubMed:12642610). HRAS signaling contributes to this process by regulating G3BP dephosphorylation (PubMed:12642610). .
    Clonality
    • Monoclonal
    Conjugate
    • Unconjugated
    Formulation PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
    Gene ID 10146 (Human) | 27041 (Mouse)
    Host Rabbit
    Isotype
    • IgG
    • Kappa
    Molecular Weight Calculated: 52 kDa | Observed: 68 kDa
    Product Type
    • Monoclonal Antibody
    • Primary Antibodies
    Reactivity
    • Human
    • Mouse
    • Rat
    Storage -15°C to -25°C/1 year(Do not lower than -25°C)
    Target G3BP1
    Antibody

    Product Overview

    U-Blot® G3BP1 Rabbit Monoclonal Antibody is a rabbit monoclonal antibody from UcallM Biosciences Inc, raised against G3BP1. It has been validated for Western Blot, Immunohistochemistry, Immunofluorescence, Immunoprecipitation, ELISA and reacts with Human, Mouse, Rat.

    Validated Applications

    Target G3BP1
    Host Rabbit
    Clonality Monoclonal
    Clone PT1039R
    Isotype IgG, Kappa
    Conjugate Unconjugated
    Reactivity Human, Mouse, Rat
    Applications Western Blot, Immunohistochemistry, Immunofluorescence, Immunoprecipitation, ELISA
    Purification Protein A
    Specificity Endogenous
    Molecular Weight Calculated: 52 kDa | Observed: 68 kDa
    UniProt / Swiss-Prot Q13283 (Human) | P97855 (Mouse)

    Recommended dilutions: IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200

    Immunogen / Antigen

    Ras GTPase-activating protein-binding protein 1

    Reactivity Notes

    Confirmed cross-reactivity: Human, Mouse, Rat. Confirm suitability for untested species before use.

    Scientific Background

    This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]

    Safety & Handling

    For Research Use Only (RUO). Not for diagnostic or therapeutic use. Store as indicated: -15°C to -25°C/1 year(Do not lower than -25°C)
    What applications is this antibody validated for?

    This antibody is validated for Western Blot, Immunohistochemistry, Immunofluorescence, Immunoprecipitation, ELISA. Recommended dilutions: IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200

    What species does it react with?

    Confirmed reactivity: Human, Mouse, Rat. Other species should be validated by the user.

    Is this antibody conjugated?

    Conjugate: Unconjugated.

    How should it be stored?

    Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)

    What is the clone number?

    Clone PT1039R.

    Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.

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