| Field | Specification |
|---|---|
| Alternative Names | GSK3B;Glycogen synthase kinase-3 beta;GSK-3 beta;Serine/threonine-protein kinase GSK3B |
| Antigen | |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Conjugate | |
| Formulation | |
| Gene ID | |
| Host | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GSK3B. AA range:1-50 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Product Overview
U-Blot® GSK3β Rabbit Polyclonal Antibody is a rabbit polyclonal antibody from UcallM Biosciences Inc, raised against GSK3β. It has been validated for Immunofluorescence, Western Blot, Immunohistochemistry, Immunoprecipitation, ELISA and reacts with Human, Mouse, Rat, Rabbit.
Validated Applications
| Target | GSK3β |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat, Rabbit |
| Applications | Immunofluorescence, Western Blot, Immunohistochemistry, Immunoprecipitation, ELISA |
| Purification | Affinity Purified |
| Specificity | GSK3β Polyclonal Antibody detects endogenous levels of GSK3β protein. |
| Molecular Weight | Observed: 47 kDa |
| UniProt / Swiss-Prot | P49841 (Human) | Q9WV60 (Mouse) | P18266 (Rat) |
Recommended dilutions: IF 1:50-200;WB 1:500-1:2000;IHC 1:100-1:300;IP 2-5 ug:mg lysate;ELISA 1:20000;Not yet tested in other applications
Immunogen / Antigen
The antiserum was produced against synthesized peptide derived from human GSK3B. AA range:1-50
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat, Rabbit. Confirm suitability for untested species before use.
Scientific Background
The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
Safety & Handling
This antibody is validated for Immunofluorescence, Western Blot, Immunohistochemistry, Immunoprecipitation, ELISA. Recommended dilutions: IF 1:50-200;WB 1:500-1:2000;IHC 1:100-1:300;IP 2-5 ug:mg lysate;ELISA 1:20000;Not yet tested in other applications
Confirmed reactivity: Human, Mouse, Rat, Rabbit. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
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