| Field | Specification |
|---|---|
| Alternative Names | 2'-5'-oligoadenylate synthase-like protein;2'-5'-OAS-related protein;2'-5'-OAS-RP;59 kDa 2'-5'-oligoadenylate synthase-like protein;Thyroid receptor-interacting protein 14;TR-interacting protein 14;TRIP-14;p59 OASL;p59OASL |
| Antigen | |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Conjugate | |
| Formulation | |
| Gene ID | |
| Host | |
| Immunogen | Synthesized peptide derived from human OASL. at AA range: 1-50 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Product Overview
U-Blot® OASL Rabbit Polyclonal Antibody is a rabbit polyclonal antibody from UcallM Biosciences Inc, raised against OASL. It has been validated for Western Blot, ELISA and reacts with Rat, Mouse.
Validated Applications
| Target | OASL |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Reactivity | Rat, Mouse |
| Applications | Western Blot, ELISA |
| Purification | Affinity Purified |
| Specificity | OASL Polyclonal Antibody detects endogenous levels of OASL |
| Molecular Weight | Observed: 60 kDa |
| UniProt / Swiss-Prot | Q15646 (Human) |
Recommended dilutions: WB 1:500-2000;ELISA 1:10000-20000
Immunogen / Antigen
Synthesized peptide derived from human OASL. at AA range: 1-50
Reactivity Notes
Confirmed cross-reactivity: Rat, Mouse. Confirm suitability for untested species before use.
Scientific Background
caution:This may not be the true ortholog of mouse OASL.,function:Does not have 2'-5'-OAS activity, but binds double-stranded RNA and DNA.,induction:By interferons.,similarity:Belongs to the 2-5A synthetase family.,similarity:Contains 2 ubiquitin-like domains.,subunit:Specifically interacts with the ligand binding domain of the thyroid receptor (TR). TRIP14 does not require the presence of thyroid hormone for its interaction. Binds MBD1.,tissue specificity:Expressed in most tissues, with the highest levels in primary blood Leukocytes and other hematopoietic system tissues, colon, stomach and to some extent in testis.
Safety & Handling
This antibody is validated for Western Blot, ELISA. Recommended dilutions: WB 1:500-2000;ELISA 1:10000-20000
Confirmed reactivity: Rat, Mouse. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
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