U-Blot® RBM8A Rabbit Polyclonal Antibody

SKU:BHA21815711
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    Overview
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    Anti-RBM8A antibody (Rabbit host, polyclonal, Unconjugated). Validated for Western Blot with reactivity to Human, Mouse, Rat.
    Clonality Polyclonal
    Host Rabbit
    Reactivity Human, Mouse, Rat
    Conjugate Unconjugated
    Isotype IgG
    Applications Western Blot
    Options selector
    Catalog no. Size
    WP4433-50 50 uL
    WP4433-100 100 uL
    Available Options

    Select the variant that best fits your experiment. Availability and lead time may vary by option.

    • Options: Size: 50 uL
    • Lead time: options listed in "Availability Content"; other statuses may take longer.
    • Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
    • Shipping: cold-chain shipment (typically with ice packs).
    • Upon receipt: store at recommended temperature as soon as possible.
    • Sales terms and conditions: Please review prior to ordering.
    Field Specification
    Antigen
    • RBM8A
    Cellular Localization Nucleus . Nucleus speckle . Cytoplasm . Nucleocytoplasmic shuttling protein (PubMed:11030346). Travels to the cytoplasm as part of the exon junction complex (EJC) bound to mRNA. Colocalizes with the core EJC, ALYREF/THOC4, NXF1 and UAP56 in the nucleus and nuclear speckles (PubMed:19324961). .
    Clonality
    • Polyclonal
    Concentration 1 mg/ml
    Conjugate
    • Unconjugated
    Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    Gene ID 9939 (Human) | 60365 (Mouse) | 295284 (Rat)
    Host Rabbit
    Immunogen Synthesized peptide derived from human RBM8A AA range: 118-168
    Isotype
    • IgG
    Molecular Weight Calculated: 19 kDa
    Product Type
    • Polyclonal Antibody
    • Primary Antibodies
    Reactivity
    • Human
    • Mouse
    • Rat
    Storage -15°C to -25°C/1 year(Do not lower than -25°C)
    Target RBM8A
    Antibody

    Product Overview

    U-Blot® RBM8A Rabbit Polyclonal Antibody is a rabbit polyclonal antibody from UcallM Biosciences Inc, raised against RBM8A. It has been validated for Western Blot and reacts with Human, Mouse, Rat.

    Validated Applications

    Target RBM8A
    Host Rabbit
    Clonality Polyclonal
    Isotype IgG
    Conjugate Unconjugated
    Reactivity Human, Mouse, Rat
    Applications Western Blot
    Purification Affinity Purified
    Specificity This antibody detects endogenous levels of RBM8A at Human/Mouse/Rat
    Molecular Weight Calculated: 19 kDa
    UniProt / Swiss-Prot Q9Y5S9 (Human) | Q9CWZ3 (Mouse) | Q27W01 (Rat)

    Recommended dilutions: WB 1:500-2000

    Immunogen / Antigen

    Synthesized peptide derived from human RBM8A AA range: 118-168

    Reactivity Notes

    Confirmed cross-reactivity: Human, Mouse, Rat. Confirm suitability for untested species before use.

    Scientific Background

    This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B; it is now thought that the RBM8B locus is a pseudogene. There are two alternate translation start codons with this gene, which result in two forms of the protein. An allele mutation and a low-frequency noncoding single-nucleotide polymorphism (SNP) in this gene cause thrombocytopenia-absent radius (TAR) syndrome. [provided by RefSeq, Jul 2013]

    Safety & Handling

    For Research Use Only (RUO). Not for diagnostic or therapeutic use. Store as indicated: -15°C to -25°C/1 year(Do not lower than -25°C)
    What applications is this antibody validated for?

    This antibody is validated for Western Blot. Recommended dilutions: WB 1:500-2000

    What species does it react with?

    Confirmed reactivity: Human, Mouse, Rat. Other species should be validated by the user.

    Is this antibody conjugated?

    Conjugate: Unconjugated.

    How should it be stored?

    Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)

    Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.

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