U-Blot® SNX3 Rabbit Polyclonal Antibody

SKU:BHA21809326
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    Overview
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    Anti-SNX3 antibody (Rabbit host, polyclonal, Unconjugated). Validated for Western Blot, ELISA, Immunohistochemistry with reactivity to Human, Mouse, Rat.
    Clonality Polyclonal
    Host Rabbit
    Reactivity Human, Mouse, Rat
    Conjugate Unconjugated
    Isotype IgG
    Applications Western Blot, ELISA, Immunohistochemistry
    Options selector
    Catalog no. Size
    WP14534-50 50 uL
    WP14534-100 100 uL
    Available Options

    Select the variant that best fits your experiment. Availability and lead time may vary by option.

    • Options: Size: 50 uL
    • Lead time: options listed in "Availability Content"; other statuses may take longer.
    • Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
    • Shipping: cold-chain shipment (typically with ice packs).
    • Upon receipt: store at recommended temperature as soon as possible.
    • Sales terms and conditions: Please review prior to ordering.
    Field Specification
    Alternative Names SNX3;Sorting nexin-3;Protein SDP3
    Antigen
    • Sorting nexin-3
    Cellular Localization Early endosome . Cytoplasmic vesicle, phagosome . Colocalizes to clathrin-coated endosomal vesicles morphologically distinct from retromer-decorated non-branched endosomal tubule structures (PubMed:21725319) Colocalizes with EEA1 on nascent phagosomes in dendritic cells but competes with EEA1 for binding to phagosomal membrane (PubMed:23237080). In the case of Salmonella enterica infection localizes to Salmonella-containing vacuoles (SCVs) from which SNX3-containing tubules form 30-60 min after infection (PubMed:20482551). .
    Clonality
    • Polyclonal
    Concentration 1 mg/ml
    Conjugate
    • Unconjugated
    Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    Gene ID 8724 (Human) | 684097 (Rat)
    Host Rabbit
    Immunogen The antiserum was produced against synthesized peptide derived from human SNX3. AA range:91-140
    Isotype
    • IgG
    Molecular Weight Observed: 18 kDa
    Product Type
    • Polyclonal Antibody
    • Primary Antibodies
    Reactivity
    • Human
    • Mouse
    • Rat
    Storage -15°C to -25°C/1 year(Do not lower than -25°C)
    Target SNX3
    Antibody

    Product Overview

    U-Blot® SNX3 Rabbit Polyclonal Antibody is a rabbit polyclonal antibody from UcallM Biosciences Inc, raised against SNX3. It has been validated for Western Blot, ELISA, Immunohistochemistry and reacts with Human, Mouse, Rat.

    Validated Applications

    Target SNX3
    Host Rabbit
    Clonality Polyclonal
    Isotype IgG
    Conjugate Unconjugated
    Reactivity Human, Mouse, Rat
    Applications Western Blot, ELISA, Immunohistochemistry
    Purification Affinity Purified
    Specificity SNX3 Polyclonal Antibody detects endogenous levels of SNX3 protein.
    Molecular Weight Observed: 18 kDa
    UniProt / Swiss-Prot O60493 (Human) | O70492 (Mouse) | Q5U211 (Rat)

    Recommended dilutions: WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000

    Immunogen / Antigen

    The antiserum was produced against synthesized peptide derived from human SNX3. AA range:91-140

    Reactivity Notes

    Confirmed cross-reactivity: Human, Mouse, Rat. Confirm suitability for untested species before use.

    Scientific Background

    This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like most family members. This protein interacts with phosphatidylinositol-3-phosphate, and is involved in protein trafficking. A pseudogene of this gene is present on the sex chromosomes. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]

    Safety & Handling

    For Research Use Only (RUO). Not for diagnostic or therapeutic use. Store as indicated: -15°C to -25°C/1 year(Do not lower than -25°C)
    What applications is this antibody validated for?

    This antibody is validated for Western Blot, ELISA, Immunohistochemistry. Recommended dilutions: WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000

    What species does it react with?

    Confirmed reactivity: Human, Mouse, Rat. Other species should be validated by the user.

    Is this antibody conjugated?

    Conjugate: Unconjugated.

    How should it be stored?

    Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)

    Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.

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