| Field | Specification |
|---|---|
| Alternative Names | STAT1;Signal transducer and activator of transcription 1-alpha/beta;Transcription factor ISGF-3 components p91/p84 |
| Antigen | |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Conjugate | |
| Formulation | |
| Gene ID | |
| Host | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human STAT1. AA range:694-743 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Product Overview
U-Blot® STAT1 Rabbit Polyclonal Antibody is a rabbit polyclonal antibody from UcallM Biosciences Inc, raised against STAT1. It has been validated for Immunofluorescence, Western Blot, Immunohistochemistry, Immunoprecipitation, ELISA and reacts with Human, Mouse, Rat, Chicken.
Validated Applications
| Target | STAT1 |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat, Chicken |
| Applications | Immunofluorescence, Western Blot, Immunohistochemistry, Immunoprecipitation, ELISA |
| Purification | Affinity Purified |
| Specificity | Stat1 Polyclonal Antibody detects endogenous levels of Stat1 protein. |
| Molecular Weight | Observed: 87 kDa |
| UniProt / Swiss-Prot | P42224 (Human) | P42225 (Mouse) |
Recommended dilutions: IF 1:50-200;WB 1:500-1:2000;IHC 1:100-1:300;IP 1:200;ELISA 1:10000;Not yet tested in other applications
Immunogen / Antigen
The antiserum was produced against synthesized peptide derived from human STAT1. AA range:694-743
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat, Chicken. Confirm suitability for untested species before use.
Scientific Background
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Safety & Handling
This antibody is validated for Immunofluorescence, Western Blot, Immunohistochemistry, Immunoprecipitation, ELISA. Recommended dilutions: IF 1:50-200;WB 1:500-1:2000;IHC 1:100-1:300;IP 1:200;ELISA 1:10000;Not yet tested in other applications
Confirmed reactivity: Human, Mouse, Rat, Chicken. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
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