Biosimilar Antibodies

Research-grade recombinant biosimilar antibodies and receptor-trap proteins that reproduce the binding specificity of reference biologic drugs — for use as binding reagents, functional blocking tools, and PK/ADA assay controls. For Research Use Only.

1396Products
1396 products
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Target: PVRIG
Primary Antibody Western Blot
From $99.00
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Target: PD-1
Primary Antibody Western Blot
From $99.00
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Target: PD-1
Primary Antibody Western Blot
From $99.00
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Target: PCSK9
Primary Antibody Western Blot
From $99.00
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Target: PD-1
Primary Antibody Western Blot
From $99.00
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Target: PD-1
Primary Antibody Western Blot
From $99.00
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Target: PD-1
Primary Antibody Western Blot
From $99.00
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Target: PD-1
Primary Antibody Western Blot
From $99.00
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Target: PD-1
Primary Antibody Western Blot
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Target: PD-L1
Primary Antibody Western Blot
From $99.00
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Target: PD-1
Primary Antibody Western Blot
From $99.00
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Target: SEMA4D
Primary Antibody Western Blot
From $99.00
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Biotinylated Anti-PD-1(nivolumab biosimilar) mAb – Figure 1 of 1
Target: PD-1
Primary Antibody ELISA
From $99.00
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Target: PCSK9
Primary Antibody Western Blot
From $99.00
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Target: PD-1
Primary Antibody Western Blot
From $99.00
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Target: OX40
Primary Antibody Western Blot
From $99.00
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Target: PDGFRA
Primary Antibody Western Blot
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Target: Mesothelin
Primary Antibody Western Blot
From $99.00
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Target: SIRPα
Primary Antibody Western Blot
From $99.00
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Target: NGF
Primary Antibody Western Blot
From $99.00
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Target: PD-L1
Primary Antibody Western Blot
From $99.00
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Target: PD-1
Primary Antibody Western Blot
From $99.00
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Target: OX40
Primary Antibody Western Blot
From $99.00
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Target: PD-1
Primary Antibody Western Blot
From $99.00
Regular price From $99.00
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Target: PCSK9
Primary Antibody Western Blot
From $99.00
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Target: PD-1
Primary Antibody Western Blot
From $99.00
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Target: PD-L1
Primary Antibody Western Blot
From $99.00
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Target: SNCA
Primary Antibody Western Blot
From $99.00
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Target: PD-1
Primary Antibody Western Blot
From $99.00
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Target: PD-1
Primary Antibody Western Blot
From $99.00
Regular price From $99.00
In Stock at Manufacturer
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Target: SIRPα
Primary Antibody Western Blot
From $99.00
Regular price From $99.00
In Stock at Manufacturer
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Target: PCSK9
Primary Antibody Western Blot
From $99.00
Regular price From $99.00
In Stock at Manufacturer
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Target: PD-1
Primary Antibody Western Blot
From $99.00
Regular price From $99.00
In Stock at Manufacturer
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Target: PD-1
Primary Antibody Western Blot
From $99.00
Regular price From $99.00
In Stock at Manufacturer
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Target: PD-L1
Primary Antibody Western Blot
From $99.00
Regular price From $99.00
In Stock at Manufacturer
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Target: PD-1
Primary Antibody Western Blot
From $99.00
Regular price From $99.00
In Stock at Manufacturer

About Biosimilar Antibodies

This collection brings together research-grade recombinant antibodies (and receptor-trap fusion proteins) that reproduce the antigen-binding specificity of clinically important reference biologics — anti-TNF, anti-VEGF, anti-PD-1/PD-L1, anti-HER2, anti-CD20 and many more. Each reagent binds the same target as its reference drug, so it can serve as a positive control, a functional blocking/neutralizing tool, a binding reagent, and a reference standard in pharmacokinetic (PK) and anti-drug-antibody (ADA) bioanalysis. All products are For Research Use Only (RUO) and are not the licensed therapeutic products.

Choosing how to work with a reference biologic: three complementary reagents

A biosimilar research antibody is one of three reagents used to study or measure a biologic drug. They are complementary, not interchangeable — most immunogenicity and PK workflows use all three.

DimensionBiosimilar antibody (this collection)Anti-idiotypic antibodyPK / ADA ELISA kit
What it isRecombinant copy of the drug's variable regionAntibody raised against the drug's paratope/idiotypeReady-to-run immunoassay
What it bindsThe drug's antigen (e.g. TNF-α, PD-1, HER2)The reference/biosimilar drug itselfThe drug, or anti-drug antibodies, in a sample
Primary usePositive control, blocking/neutralization, binding reagentCapture or detect the drug; ADA bridging assaysQuantify drug level (PK) or immunogenicity (ADA)
Reads outBinding & function (ELISA, SPR/BLI, flow, neutralization)Drug concentration when paired in an assayConcentration from a standard curve
Best forAssay development, functional studies, controlsBuilding a custom PK or ADA assayRoutine sample quantification
FormatPurified protein (mAb, Fab, fusion or ADC)Purified antibodyMicroplate kit

How to read this: Use the biosimilar antibody as your positive control and functional tool. To measure the drug in samples, pair it with an anti-idiotypic antibody to build a PK or ADA assay, or use a ready-made ELISA kit for routine quantification. If you are characterizing binding or blocking activity, start here; if you are quantifying drug or anti-drug-antibody levels, add the matching kit.

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