| Field | Specification |
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| Mfr No | |
| Activity | |
| Cas No. | |
| Molecular Weight | |
| Product Type | |
| Signaling Pathway | |
| SMILES | |
| Target |
Compound Overview
HIF-IN-1 (CAS 2393928-76-0) is a research-grade small molecule supplied by TargetMol.
Physical Properties
| CAS Number | 2393928-76-0 |
|---|---|
| Molecular Formula | C17H12N2O |
| Molecular Weight | 260.29 g/mol |
| SMILES | O=C1C2=C(C=3C1=CC=CC3)C=NN2C4=CC=C(C)C=C4 |
| Form | Solid |
| Shipping | Room Temperature (RT) |
Biological Activity
HIF-IN-1 is a potent inhibitor of hypoxia-inducible factor (HIF-1), which is associated with tumor and cancer cell proliferation and inhibits HIF-1alpha protein aggregation.
Target(s): HIF
Signaling pathway(s): Chromatin/Epigenetic, Angiogenesis
Safety & Regulatory
For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.
Try the following steps: (1) warm the DMSO solvent to 37–50 °C before adding the compound; (2) vortex vigorously for 30 seconds then bath-sonicate for 1–2 minutes; (3) if still undissolved, prepare a more dilute stock. Note that maximum solubility values are reference conditions — actual solubility can vary with temperature, solvent lot, and compound batch. Contact BioHippo support if dissolution problems persist.
Stock concentration (mM) = [mass (mg) × 1000] / [MW (g/mol) × volume (mL)]. Example: to prepare 10 mM stock from 5 mg of a 500 g/mol compound: volume = (5 × 1000) / (500 × 10) = 1 mL DMSO. For working solutions, dilute the DMSO stock into assay buffer: C₁V₁ = C₂V₂. For a 1 µM working solution from a 10 mM stock in a 1 mL assay volume, add 0.1 µL of stock (or pre-dilute to an intermediate concentration first).
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
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