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In vivo–grade custom AAV, lentivirus & adenovirus produced in the USA.

SignaGen Laboratories Verified partner

SignaGen Laboratories is a US-based gene delivery company specializing in custom and pre-made AAV, lentiviral, and adenoviral vectors, plus DNA/siRNA transfection reagents and stable cell line development for in vitro and in vivo research.

SignaGen Laboratories is a US-based gene delivery company focused on viral vector technologies for life science and gene therapy research. It provides both custom and catalog products to academic, biotech, and pharmaceutical laboratories.

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The portfolio spans recombinant AAV, lentiviral, and adenoviral vectors across multiple serotypes, together with DNA and siRNA transfection reagents (including PolyJet and GenJet) and stable cell line development services.

SignaGen operates a full-service model, supporting projects from construct design through viral packaging, purification, and quality control, with in vivo–grade material available for animal studies.

The company reports over a decade of operation, more than 4,000 customers, and over 7,000 scientific publications citing its products, with 100% US-based manufacturing.

SignaGen Laboratories
8
Product lines
United States
Origin
Custom AAV, Lentiviral & Adenoviral Production
Lead time
United States · Ships worldwide via BioHippo
Why work with them

What makes SignaGen Laboratories different

Custom viral vector production

SignaGen designs and packages recombinant AAV, lentiviral, and adenoviral vectors to customer specifications. Services cover cloning, packaging, purification, and titer determination for in vitro and in vivo applications.

In vivo–grade quality

Vectors are available at high, guaranteed titers suitable for animal studies. SignaGen states pre-made AAVs at >1 × 10¹³ VG/mL, lentiviruses at >1 × 10⁹ TU/mL (RCL-free), and adenoviruses at >1 × 10¹⁰ PFU/mL (RCA-free).

Catalog and custom options

Researchers can order ready-to-use pre-made viral vectors and reporter constructs, or commission fully custom packaging. Multiple AAV serotypes, including AAV-DJ and Retrograde, support neuroscience, gene editing, and gene therapy research.

Key techniques

Where they're strong

SignaGen supports viral gene delivery and transfection workflows across in vitro and in vivo research.

AAV Packaging & PurificationLentiviral ProductionAdenoviral ProductionMulti-Serotype AAV (incl. DJ & Retrograde)DNA & siRNA TransfectionStable Cell Line DevelopmentCRISPR DeliveryTiter & QC Assays
Catalog scope

Product lines & services

SignaGen combines a catalog of pre-made viral vectors and transfection reagents with fully custom vector production services.

R

Recombinant AAV Vectors (Custom & Pre-made)

L

Lentiviral Vectors (Custom & Pre-made)

A

Adenoviral Vectors (Custom & Pre-made)

I

In Vivo–Grade Viral Vectors

D

DNA & siRNA Transfection Reagents (PolyJet, GenJet)

S

Stable Cell Line Development

C

CRISPR / Genome-Editing Delivery

V

Viral Vector Purification & QC

Quality & logistics

QC, documentation & shipping

Quality control & documentation

SignaGen provides guaranteed-titer, purity-tested viral vectors with supporting QC documentation.

Quality control
Performed & documented
In vivo–grade AAV guaranteed at >1 × 10¹³ VG/mL
Lentivirus guaranteed at >1 × 10⁹ TU/mL, RCL-free
Adenovirus guaranteed at >1 × 10¹⁰ PFU/mL, RCA-free
Documentation
Available on request
Certificate of Analysis MSDS / SDS HPLC report Quality Policy

Lead time & shipping

Delivery timelines depend on product type and level of customization.

Pre-made catalog vectors and reagents ship quickly; custom production follows project timelines
100% US-based manufacturing
Temperature-controlled shipping for viral vectors and reagents

Request a quote from SignaGen Laboratories

Tell us your target and application — a BioHippo scientist will shortlist options and pricing, usually within one business day.

One vendor, one PO — sourced through BioHippo
COA / MSDS / QC on request
Bulk & custom pricing available