Circular RNAs encoding reporter proteins, engineered for enhanced exonuclease resistance and prolonged expression compared with linear mRNA.
| Image | Product | Product Type | Application | Price | Status | ACTION |
|---|---|---|---|---|---|---|
|
Target: mCherry-HQ | DNA&RNA, RNA, circRNA | Gene Expression |
$1,319.00
Regular price
$1,319.00
|
In Stock at Manufacturer: This item is available from our manufacturing partner and ships after a short processing time. | |
|
Target: Firefly Luciferase | DNA&RNA, RNA, circRNA | Gene Expression |
From $398.00
Regular price
From $398.00
|
In Stock at Manufacturer: This item is available from our manufacturing partner and ships after a short processing time. | |
|
Target: EGFP | DNA&RNA, RNA, circRNA | Gene Expression |
From $398.00
Regular price
From $398.00
|
In Stock at Manufacturer: This item is available from our manufacturing partner and ships after a short processing time. | |
|
Target: mCherry | DNA&RNA, RNA, circRNA | Gene Expression |
From $398.00
Regular price
From $398.00
|
In Stock at Manufacturer: This item is available from our manufacturing partner and ships after a short processing time. | |
|
Target: Firefly Luciferase-HQ | DNA&RNA, RNA, circRNA | Gene Expression |
$1,319.00
Regular price
$1,319.00
|
In Stock at Manufacturer: This item is available from our manufacturing partner and ships after a short processing time. | |
|
Target: EGFP-HQ | DNA&RNA, RNA, circRNA | Gene Expression |
$1,319.00
Regular price
$1,319.00
|
In Stock at Manufacturer: This item is available from our manufacturing partner and ships after a short processing time. |
Circular RNAs (circRNAs) from GenCefe Biotech — covalently closed RNA rings with no free 5′/3′ ends. With no open end for exonucleases to attack, circRNA resists degradation and sustains protein expression longer than a linear mRNA of the same sequence. The panel encodes fluorescent and luminescent reporters (EGFP, mCherry, firefly luciferase) in standard and high-purity (HQ) grades. For research use only (RUO).
circRNA is built for durable, integration-free expression — a more stable alternative to linear mRNA.
| mRNA | circRNA | siRNA | Plasmid DNA | |
|---|---|---|---|---|
| Effect | Adds protein (gain) | Adds protein (gain) | Silences gene (loss) | Adds protein (gain) |
| Site of action | Cytoplasm | Cytoplasm | Cytoplasm (RISC) | Nucleus required |
| Onset | Fast (hours) | Fast (hours) | 24–72 h | Slower |
| Duration | Transient ~1–3 d | Extended vs. mRNA | Knockdown, days | Sustained (episomal) |
| Integration | None | None | None | Low but possible |
| Best for | Transient expression, reprogramming, CAR | Durable expression, reporter & vaccine work | Target validation, knockdown screens | Cloning, stable lines, high yield |
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