Autophagy & Lysosomal Biology

Research-use ELISA kits, antibodies, and proteins for autophagy and lysosomal targets — LC3, p62/SQSTM1, Beclin-1, the ATG system, ULK1, and LAMP/cathepsin lysosomal markers.

457Products
457 products
Image Product TargetApplication(s)ReactivityPrice Status ACTION
Western blot analysis was performed using anti-SQSTM1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: K562 cell lysate
Target: SQSTM1
SQSTM1 ELISA, Immunohistochemistry, Western Blot Human, Mouse, Rat
From $268.00
Regular price From $268.00
In Stock at Manufacturer
IHC staining of FFPE human uterus with recombinant ATG5 antibody. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min and allow to cool before testing.
Target: ATG5
ATG5 Immunohistochemistry Human
From $266.77
Regular price From $266.77
In Stock at Manufacturer
SQSTM1 Polyclonal Antibody – Figure 1 of 3
Research Validated
Western Blot, Immunohistochemistry
From $147.29
Regular price From $147.29
In Stock at Manufacturer
ULK1 CRISPR Knockout 293T Cell Line | Applied Biological Materials (abm)
Cell Culture (Growth), Functional Assay
$1,802.50
Regular price $1,802.50
In Stock at Manufacturer
U-Blot® ATG12 Rabbit Polyclonal Antibody – Figure 1 of 1
New
Target: ATG12
ATG12 Western Blot Human, Mouse, Rat
From $276.04
Regular price From $276.04
In Stock at Manufacturer
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Target: Nup62
Nup62 Functional Assay (In Vitro), ELISA
From $399.64
Regular price From $399.64
Made to order
Western Blot analysis of mouse-lung mouse-muscle cells using TFEB Polyclonal Antibody
Target: TFEB
TFEB Western Blot, Immunohistochemistry, ELISA Human, Mouse
From $122.57
Regular price From $122.57
In Stock at Manufacturer
U-Blot® ULK1 (phospho S623) Rabbit mAb – Figure 1 of 1
Featured New
Target: Phospho-ULK1 (Ser623)
Phospho-ULK1 (Ser623) Western Blot Human
From $296.64
Regular price From $296.64
In Stock at Manufacturer
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Target: LIPA
LIPA Functional Assay (In Vitro), ELISA
From $230.72
Regular price From $230.72
Made to order
U-Blot® ULK1 (Phospho Ser555) Rabbit Polyclonal Antibody – Figure 1 of 1
New
Target: ULK1
ULK1 Western Blot Human, Mouse
From $296.64
Regular price From $296.64
In Stock at Manufacturer
TFEB CRISPR Knockout 293T Cell Line | Applied Biological Materials (abm)
Cell Culture (Growth), Functional Assay
$1,802.50
Regular price $1,802.50
In Stock at Manufacturer
TFEB antibody western blot analysis in HepG2 lysate. Expected molecular weight: 53-60 kDa (unmodified), 65-70 kDa (modified).
Target: TFEB
TFEB Western Blot, ELISA Human
From $211.15
Regular price From $211.15
In Stock at Manufacturer
Recombinant Human Autophagy Related 5 – Figure 1 of 1
Target: APG5L
APG5L Functional Assay (In Vitro), ELISA
From $61.80
Regular price From $61.80
In Stock at Manufacturer
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Target: TFEB
TFEB Functional Assay (In Vitro), ELISA
From $263.68
Regular price From $263.68
ULK1 antibody western blot analysis in U251 lysate. Predicted molecular weight: 112-150 kDa
Target: ULK1
ULK1 Western Blot, ELISA Human
From $211.15
Regular price From $211.15
In Stock at Manufacturer
Rat Beclin 1, BECN1 ELISA Kit
Target: BECN1
BECN1 ELISA Rat
$458.00
Regular price $458.00
In Stock at Manufacturer
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Target: Scarb2
Scarb2 Functional Assay (In Vitro), ELISA
From $315.18
Regular price From $315.18
ULK1 Antibody – Figure 1 of 1
Target: ULK1
ULK1 Immunohistochemistry, ELISA Human, Mouse
From $122.57
Regular price From $122.57
In Stock at Manufacturer
Recombinant Human Beclin 1, Autophagy Related – Figure 1 of 1
Target: BECLIN1
BECLIN1 Enzyme Activity
From $61.80
Regular price From $61.80
In Stock at Manufacturer
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Target: ATG8
ATG8 Functional Assay (In Vitro), ELISA
From $399.64
Regular price From $399.64
Made to order
ULK1 Antibody, HRP conjugated – Figure 1 of 1
Target: ULK1
ULK1 ELISA Human
From $170.98
Regular price From $170.98
In Stock at Manufacturer
sqstm1 KO MEF Expressing SQSTM1ᴳ⁴²⁷ᴿ Cell Line | Applied Biological Materials (abm)
Cell Culture (Growth), Functional Assay
In Stock at Manufacturer
View
Western blot (WB) analysis of SQSTM1 polyclonal antibody at 1:500 dillution
Lane1:Hela whole cell lysate(40μg)
Lane2:NIH-3T3 whole cell lysate(30μg)
Lane3:PC12 whole cell lysate(40μg)
Western Blot, Immunohistochemistry, Immunoprecipitation, Immunofluorescence Human, Mouse, Rat
From $162.74
Regular price From $162.74
In Stock at Manufacturer
Fluorescent image of Chloroquine treated U251 cells stained with phospho-ULK1 antibody at 1:200. Immunoreactivity is localized to autophagic vacuoles in the cytoplasm.
Target: ULK1
ULK1 Immunofluorescence, Dot Blot, ELISA Human
From $211.15
Regular price From $211.15
In Stock at Manufacturer
Mouse LAMP2 (Lysosome-associated membrane glycoprotein 2) ELISA Kit
Target: LAMP2
LAMP2 ELISA Mouse
$520.00
Regular price $520.00
In Stock at Manufacturer
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Target: ATG2A
ATG2A Functional Assay (In Vitro), ELISA
From $230.72
Regular price From $230.72
Made to Order
Rat Becn1 (Beclin-1) ELISA Kit
Target: Becn1
Becn1 ELISA Rat
$520.00
Regular price $520.00
In Stock at Manufacturer
TFEB Antibody – Figure 1 of 1
Target: TFEB
TFEB ELISA, Western Blot, Immunoprecipitation, Immunohistochemistry, Immunofluorescence Human, Mouse, Rat
$618.00
Regular price $618.00
In Stock at Manufacturer
Recombinant Human ATG7 Protein, N-His
Target: ATG7
ATG7 ELISA, Immunogen, SDS-PAGE, Western Blot
From $411.00
Regular price From $411.00
ULK1 antibody western blot analysis in HeLa lysate. Predicted molecular weight: 112-150 kDa.
Target: ULK1
ULK1 Western Blot, ELISA Human
From $211.15
Regular price From $211.15
In Stock at Manufacturer
Western Blot
Positive WB detected in: HeLa whole cell lysate(30µg) , HepG2 whole cell lysate(30µg) , PC-3 whole cell lysate(30µg) , COLO205 whole cell lysate(30µg) , HEK293 whole cell lysate(30µg) 
All lanes: SQSTM1 antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 48 kDa
Observed band size: 62 kDa
Exposure time: 2min
Target: SQSTM1
SQSTM1 ELISA, Western Blot Human
From $216.30
Regular price From $216.30
In Stock at Manufacturer
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using TF2H1 Antibody. The picture on the right is blocked with the synthesized peptide.
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA Human, Mouse
From $192.40
Regular price From $192.40
In Stock at Manufacturer
Rat ATG13 ( autophagy protein 13 ) ELISA Kit
Target: ATG13
ATG13 ELISA Rat
$520.00
Regular price $520.00
In Stock at Manufacturer
Western blot testing of 1) human HEK293 and 2) rat PC-12 cell lysate with ULK1 antibody. Predicted molecular weight: 112-150 kDa.
Target: ULK1
ULK1 Western Blot Human, Rat
$462.47
Regular price $462.47
In Stock at Manufacturer
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Target: Pla2g15
Pla2g15 Functional Assay (In Vitro), ELISA
From $195.70
Regular price From $195.70
Human P62/SQSTM1 (Sequestosome-1) ELISA Kit
Target: P62/SQSTM1
P62/SQSTM1 ELISA Human
$520.00
Regular price $520.00
In Stock at Manufacturer

About Autophagy & Lysosomal Biology

Antibodies, assay kits, and proteins for studying autophagy and lysosomal biology. The category covers the core autophagy machinery (LC3/ATG8, ATG5–ATG12, Beclin-1, ULK1), the selective-autophagy adaptor p62/SQSTM1, upstream regulators (mTOR, AMPK), and lysosomal markers and hydrolases (LAMP1/2, cathepsins). Use it to source validated reagents for autophagy-flux, lysosomal-function, and protein-degradation research across human and preclinical species.

About Autophagy & Lysosomal Biology

Autophagy and lysosomal biology cover the cell’s catabolic machinery — the pathways that capture damaged proteins, aggregates, and whole organelles and route them to the lysosome for degradation and nutrient recycling, especially under nutrient or energy stress. This collection gathers ELISA kits, antibodies, and proteins for the core autophagy and lysosomal targets: LC3, SQSTM1/p62, Beclin-1, the ATG conjugation system (ATG5/ATG7/ATG12), ULK1, and lysosomal membrane and enzyme markers (LAMP1/2, cathepsins, GAA).

Reading the cell’s disposal systems: Autophagy vs Ubiquitin–Proteasome vs Apoptosis

Three degradation systems keep a cell healthy, and they answer different questions. Autophagy/lysosomal degradation is the system in this collection; the table shows when to reach for it versus its two siblings.

DimensionAutophagy & LysosomalProtein Quality Control (Ubiquitin–Proteasome)Apoptosis & Cell Death
What it removesBulk cytoplasm, aggregates, whole organelles (e.g. mitophagy)Individual poly-ubiquitin-tagged proteinsThe entire cell (programmed death)
Degradation siteLysosome26S proteasomeExecutioner caspases (no single organelle)
Core machineryATG proteins, LC3 lipidation, autophagosome → lysosomeE1/E2/E3 ligases, proteasome, chaperonesBcl-2 family, caspases, cytochrome c
Key markersLC3-II, SQSTM1/p62, Beclin-1, LAMP1/2Ubiquitin, proteasome subunits, HSPsCleaved caspase-3, Annexin V, cytochrome c
Typical triggerNutrient/energy stress, damaged organellesMisfolded or excess proteinsIrreparable damage, death signals
OutcomeSurvival & recyclingProteostasisCell elimination
Watch-outsp62 falls with flux but rises when flux is blocked — interpret with LC3 turnover (± lysosomal inhibitor), not a single snapshotUbiquitin signal is not proof of proteasomal fateEarly vs late markers differ; use a time course

How to read this: use Autophagy & Lysosomal when the target is bulk or organelle recycling routed to the lysosome. When your target is a single ubiquitin-tagged protein, use Protein Quality Control; when the readout is whether the cell lives or dies, use Apoptosis & Cell Death. The systems cross-talk — blocking autophagy can tip stressed cells toward apoptosis — so many studies assay more than one.

Recommended autophagy & lysosomal kits

Human Beclin-1 (BECN1) ELISA Kit

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Human SQSTM1 / p62 ELISA Kit

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Human ATG7 ELISA Kit

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Human LAMP1 ELISA Kit

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Related reading

Monitoring autophagic flux: LC3-II and p62 together
Selective autophagy: mitophagy and aggrephagy markers
Lysosomal function readouts (LAMP, cathepsins)

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