Autophagy & Lysosomal Biology

Research-use ELISA kits, antibodies, and proteins for autophagy and lysosomal targets — LC3, p62/SQSTM1, Beclin-1, the ATG system, ULK1, and LAMP/cathepsin lysosomal markers.

457Products
457 products
Image Product TargetApplication(s)ReactivityPrice Status ACTION
Recombinant Human LAMP1
Target: CD107
CD107 Western Blot, ELISA
From $374.40
Regular price From $374.40
In Stock at Manufacturer
Recombinant Human ATPase Transporting, Lysosomal V1 Subunit F – Figure 1 of 1
Target: ATP6V1F
ATP6V1F Functional Assay (In Vitro), ELISA
From $61.80
Regular price From $61.80
In Stock at Manufacturer
TFEB Antibody, Biotin conjugated – Figure 1 of 1
Target: TFEB
TFEB ELISA Human
From $170.98
Regular price From $170.98
In Stock at Manufacturer
Rat ULK1 (Serine/threonine-protein kinase) ELISA Kit
Target: Serine/threonine-protein kinase
Serine/threonine-protein kinase ELISA, Enzyme Activity Rat
$520.00
Regular price $520.00
In Stock at Manufacturer
Human TFEB (Transcription factor EB) ELISA Kit
Target: TFEB
TFEB ELISA Human
$520.00
Regular price $520.00
In Stock at Manufacturer
Human Lysosomal Alpha-mannosidase, MAN2B1 ELISA Kit
Target: MAN2B1
MAN2B1 ELISA Human
$458.00
Regular price $458.00
In Stock at Manufacturer
IHC staining of FFPE zebrafish cerebellum tissue with Zebrafish Atg5 antibody, HRP secondary and DAB substrate. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.
Target: Atg5
Atg5 Immunohistochemistry Zebrafish
$555.17
Regular price $555.17
In Stock at Manufacturer
Recombinant Human Autophagy Related 10 – Figure 1 of 1
Target: APG10L
APG10L Functional Assay (In Vitro), ELISA
From $61.80
Regular price From $61.80
In Stock at Manufacturer
Human Lysosomal Alpha-glucosidase, GAA ELISA Kit
Target: GAA
GAA ELISA Human
$458.00
Regular price $458.00
In Stock at Manufacturer
ULK1 Antibody, Biotin conjugated – Figure 1 of 1
Target: ULK1
ULK1 ELISA Human
From $170.98
Regular price From $170.98
In Stock at Manufacturer
Phospho-ULK1 (Ser450) Antibody – Figure 1 of 5
Immunofluorescence, Immunohistochemistry, Western Blot Human, Mouse
From $360.50
Regular price From $360.50
In Stock at Manufacturer
Flow Cytometry analysis of 293T cells using anti-RILPL1 antibody. Overlay histogram showing 293T cells stained with (Blue line). To facilitate intracellular staining, cells were fixed with 4% paraformaldehyde and permeabilized with permeabilization buffer. The cells were blocked with 10% normal goat serum. And then incubated with rabbit anti-RILPL1 antibody (1 ug/million cells) for 30 min at 20oC.
Target: RILPL1
RILPL1 Western Blot, ELISA Human, Rat
$462.47
Regular price $462.47
In Stock at Manufacturer
U-Blot® ULK1 (Phospho Ser638) Rabbit Polyclonal Antibody – Figure 1 of 1
New
Target: ULK1
ULK1 Western Blot Human, Mouse
From $296.64
Regular price From $296.64
In Stock at Manufacturer
SQSTM1 antibody western blot analysis in HeLa lysate. Observed molecular weight ~62 kDa.
Target: SQSTM1
SQSTM1 Western Blot, ELISA Human
From $211.15
Regular price From $211.15
In Stock at Manufacturer
Recombinant Mouse Lysosomal-Associated Membrane Protein 2 – Figure 1 of 1
Target: LAMP2
LAMP2 Functional Assay (In Vitro), ELISA
From $61.80
Regular price From $61.80
In Stock at Manufacturer
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Target: LAMP5
LAMP5 Functional Assay (In Vitro), ELISA
From $263.68
Regular price From $263.68
Made to order
Recombinant Human Lysosomal-Associated Membrane Protein 2 – Figure 1 of 1
Target: LAMP2
LAMP2 Functional Assay (In Vitro), ELISA
From $61.80
Regular price From $61.80
In Stock at Manufacturer
U-Blot® TFIIH p62 Rabbit Polyclonal Antibody – Figure 1 of 1
New
Target: TFIIH p62
TFIIH p62 Western Blot, Immunohistochemistry, Immunofluorescence, ELISA Human, Mouse
From $276.04
Regular price From $276.04
In Stock at Manufacturer
Mouse SQSTM1(Sequestosome 1) ELISA Kit
Target: SQSTM1
SQSTM1 ELISA Mouse
From $416.00
Regular price From $416.00
In Stock at Manufacturer
Mouse NUP62 (nucleoporin p62) ELISA Kit
Target: NUP62
NUP62 ELISA Mouse
$520.00
Regular price $520.00
In Stock at Manufacturer
Immunofluorescent staining of human lung cancer tissue with p62 antibody (red) at 1ug/ml and DAPI counterstain. HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min and allow to cool before testing.
Target: P62
P62 Immunohistochemistry, Immunofluorescence, Western Blot Human, Mouse, Rat
$462.47
Regular price $462.47
In Stock at Manufacturer
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Target: Becn1
Becn1 Functional Assay (In Vitro), ELISA
From $399.64
Regular price From $399.64
In Stock at Manufacturer
Mouse Anti-LAMP1 Antibody [Ly1C6] used in Immunocytochemistry/Immunofluorescence (ICC/IF) on Human transfected HeLa cells (SMC-140)
Target: LAMP1
LAMP1 Western Blot, Immunofluorescence, Immunoprecipitation Human, Mouse, Rat, Hamster
From $335.78
Regular price From $335.78
In Stock at Manufacturer
SQSTM1 Antibody, Biotin conjugated – Figure 1 of 1
Target: SQSTM1
SQSTM1 ELISA Human
From $170.98
Regular price From $170.98
In Stock at Manufacturer
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Target: TASL
TASL Functional Assay (In Vitro), ELISA
From $315.18
Regular price From $315.18
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Target: TFEB
TFEB Functional Assay (In Vitro), ELISA
From $315.18
Regular price From $315.18
Rat LAMP2(Lysosomal Associated Membrane Protein 2) ELISA Kit
Target: LAMP2
LAMP2 ELISA Rat
From $416.00
Regular price From $416.00
In Stock at Manufacturer
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Target: Nup62
Nup62 Functional Assay (In Vitro), ELISA
From $543.84
Regular price From $543.84
Made to order
Western blot testing of human lung lysate with TFEB antibody at 1ug/ml. Expected molecular weight: 53-60 kDa (unmodified), 65-70 kDa (modified).
Target: TFEB
TFEB Western Blot, ELISA Human
$489.25
Regular price $489.25
In Stock at Manufacturer
Western blot
All lanes: Transcription factor EB antibody at 3ug/ml
Lane 1: Jurkat whole cell lysate
Lane 2: Mouse brain tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 53, 44 kDa
Observed band size: 53 kDa
Target: TFEB
TFEB ELISA, Western Blot, Immunohistochemistry Human, Mouse
From $170.98
Regular price From $170.98
In Stock at Manufacturer
Dot blot analysis of phospho Beclin 1 antibody. 50ng of phos-peptide or nonphos-peptide per dot were spotted.
Target: BECN1
BECN1 Dot Blot, ELISA Human
From $211.15
Regular price From $211.15
In Stock at Manufacturer
Western blot testing of human 1) K562, 2) HEK293, 3) HeLa, 4) Jurkat, 5) HepG2, 6) Raji, 7) A549 and 8) SW620 cell lysate with TFEB antibody. A major band is detected at approximately 65 kDa in all samples, which migrates higher than the predicted 53 kDa size and reflects the phosphorylated forms of TFEB. Several cell lines show a faint lower band around 60 kDa, consistent with a less phosphorylated TFEB species.
Target: TFEB
TFEB Western Blot, ELISA Human
$462.47
Regular price $462.47
In Stock at Manufacturer
Recombinant Human Transcription factor EB (TFEB) – Figure 1 of 1
Target: TFEB
TFEB Functional Assay (In Vitro), ELISA
From $263.68
Regular price From $263.68
Anti-APG5L/ATG5 Antibody Picoband®
Target: ATG5
ATG5 Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry, ELISA Human, Mouse, Rat
From $381.10
Regular price From $381.10
In Stock at Manufacturer
SQSTM1 CRISPR Knockout 293T Cell Line | Applied Biological Materials (abm)
Cell Culture (Growth), Functional Assay
$1,802.50
Regular price $1,802.50
In Stock at Manufacturer
SQSTM1 antibody – Figure 1 of 4
Research Validated
Target: SQSTM1
SQSTM1 ELISA, Western Blot, Immunohistochemistry, Immunofluorescence Human, Mouse, Rat
$338.00
Regular price $338.00
In Stock at Manufacturer

About Autophagy & Lysosomal Biology

Antibodies, assay kits, and proteins for studying autophagy and lysosomal biology. The category covers the core autophagy machinery (LC3/ATG8, ATG5–ATG12, Beclin-1, ULK1), the selective-autophagy adaptor p62/SQSTM1, upstream regulators (mTOR, AMPK), and lysosomal markers and hydrolases (LAMP1/2, cathepsins). Use it to source validated reagents for autophagy-flux, lysosomal-function, and protein-degradation research across human and preclinical species.

About Autophagy & Lysosomal Biology

Autophagy and lysosomal biology cover the cell’s catabolic machinery — the pathways that capture damaged proteins, aggregates, and whole organelles and route them to the lysosome for degradation and nutrient recycling, especially under nutrient or energy stress. This collection gathers ELISA kits, antibodies, and proteins for the core autophagy and lysosomal targets: LC3, SQSTM1/p62, Beclin-1, the ATG conjugation system (ATG5/ATG7/ATG12), ULK1, and lysosomal membrane and enzyme markers (LAMP1/2, cathepsins, GAA).

Reading the cell’s disposal systems: Autophagy vs Ubiquitin–Proteasome vs Apoptosis

Three degradation systems keep a cell healthy, and they answer different questions. Autophagy/lysosomal degradation is the system in this collection; the table shows when to reach for it versus its two siblings.

DimensionAutophagy & LysosomalProtein Quality Control (Ubiquitin–Proteasome)Apoptosis & Cell Death
What it removesBulk cytoplasm, aggregates, whole organelles (e.g. mitophagy)Individual poly-ubiquitin-tagged proteinsThe entire cell (programmed death)
Degradation siteLysosome26S proteasomeExecutioner caspases (no single organelle)
Core machineryATG proteins, LC3 lipidation, autophagosome → lysosomeE1/E2/E3 ligases, proteasome, chaperonesBcl-2 family, caspases, cytochrome c
Key markersLC3-II, SQSTM1/p62, Beclin-1, LAMP1/2Ubiquitin, proteasome subunits, HSPsCleaved caspase-3, Annexin V, cytochrome c
Typical triggerNutrient/energy stress, damaged organellesMisfolded or excess proteinsIrreparable damage, death signals
OutcomeSurvival & recyclingProteostasisCell elimination
Watch-outsp62 falls with flux but rises when flux is blocked — interpret with LC3 turnover (± lysosomal inhibitor), not a single snapshotUbiquitin signal is not proof of proteasomal fateEarly vs late markers differ; use a time course

How to read this: use Autophagy & Lysosomal when the target is bulk or organelle recycling routed to the lysosome. When your target is a single ubiquitin-tagged protein, use Protein Quality Control; when the readout is whether the cell lives or dies, use Apoptosis & Cell Death. The systems cross-talk — blocking autophagy can tip stressed cells toward apoptosis — so many studies assay more than one.

Recommended autophagy & lysosomal kits

Human Beclin-1 (BECN1) ELISA Kit

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Human SQSTM1 / p62 ELISA Kit

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Human ATG7 ELISA Kit

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Human LAMP1 ELISA Kit

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Related reading

Monitoring autophagic flux: LC3-II and p62 together
Selective autophagy: mitophagy and aggrephagy markers
Lysosomal function readouts (LAMP, cathepsins)

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