15-OxoEDE

SKU:BHB20445831
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Overview
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15-OxoEDE (CAS 105835-44-7) is a small molecule compound supplied as a solid powder by TargetMol. For biochemical profiling and cell-based assay applications.
Activity Small Molecule Compound
CAS No. 105835-44-7
Molecular Weight
Form Solid
Shipping Room Temperature
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 25 ug, 50 ug, 100 ug, 250 ug
  • Lead time: In Stock at Manufacturer — options listed in "Availability Content"; other statuses may take longer.
  • Storage: −20 °C
  • Shipping: Room temperature (RT) shipment.
  • Upon receipt: Store at −20 °C as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Options selector
Catalog no. Size
T84564-25UG 25 ug
T84564-50UG 50 ug
T84564-100UG 100 ug
T84564-250UG 250 ug
Field Specification
Activity
  • Small Molecule Compound
Cas No. 105835-44-7
Product Type
  • Small Molecule Inhibitor
Signaling Pathway Others
Target Others

Compound Overview

15-OxoEDE (CAS 105835-44-7) is a research-grade small molecule supplied by TargetMol.

Physical Properties

CAS Number 105835-44-7
Form Solid
Shipping Room Temperature (RT)

Biological Activity

15-OxoEDE, generated through the oxidation of 15-HEDE, effectively inhibits 5-LO in RBL-1 cells with an IC50 of 55 uM, approximately half as potent as 15(S)-HEDE. Additionally, another related oxo-eicosanoid, 5-oxoETE, is produced from 5(S)-HETE via a specific dehydrogenase, exhibiting significant inflammatory activity.

Safety & Regulatory

For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.

Can high-temperature sterilization be used for inhibitors?

Most small molecule inhibitors are not compatible with autoclaving (121 °C), which can cause thermal decomposition or loss of biological activity. For sterile cell-based experiments, filter-sterilize working solutions through a 0.2 µm membrane after dilution into aqueous buffer. Verify thermal stability in the DataSheet before applying any heat treatment.

Does the product need to be protected from light?

Generally, for molecules that require light-protected storage, we will ship them in amber glass bottles.

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

  • Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
  • Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
  • QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
  • Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

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Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).

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