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Home / Biochemicals / Small Molecules

Acetyl Coenzyme A, Lithium salt

SKU : BHB21200005

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Mfr.No.	A-08, A-08-10MG, A-08-25MG, A-08-50MG, A-08-100MG
Description	Acetyl Coenzyme A (Acetyl-CoA) is a central molecule in cellular metabolism, playing a pivotal role in energy production and biosynthesis. It is generated by the acetylation of Coenzyme A (CoA) through key enzymatic processes, including pyruvate decarboxylation by pyruvate dehydrogenase, fatty acid ?-oxidation, and the catabolism of certain amino acids. Acetyl-CoA's reactive acetyl group enables its participation in various biochemical pathways, such as the tricarboxylic acid (TCA) cycle, fatty acid synthesis, and cholesterol metabolism, making it essential for cellular energy and biosynthetic processes (Pietrocola et al., 2015; Shi & Tu, 2015). Applications Acetyl Coenzyme A, Lithium Salt, is a key reagent used in metabolic research to study enzymatic functions and metabolic pathways involving acetylation. It is utilized in in vitro studies to explore the TCA cycle, where Acetyl-CoA serves as a critical substrate for citrate formation, and in the biosynthesis of fatty acids and cholesterol. It is also essential for examining acetyl-CoA's role in epigenetic regulation, such as histone acetylation, which affects gene expression and cellular differentiation (Pietrocola et al., 2015; Sibon & Strauss, 2016). Additionally, Acetyl-CoA Lithium Salt is used in research on metabolic diseases, cancer metabolism, and antimicrobial strategies, given its central role in cell metabolism and growth (Spry et al., 2008).
Appearance	White to slight yellow
Molecular Formula	C23H35N7O17P3S· 3Li
Synonyms	Acetyl-S-CoA Li3, Acetyl-CoA 3Li
Shipping	Ambient temperature (styrofoam + ice gels)
Smiles	O=C(CCNC(C(C(C)(COP([O-])(OP([O-])(OCC(C(C1O)OP(O)([O-])=O)OC1N(C2=NC=N3)C=NC2=C3N)=O)=O)C)O)=O)NCCSC(C)=O.[Li+]
Cas Number	32140-51-5
Molecular Weight	809.57 g/mol (free acid basis)
Solubility	Soluble in water
Origin	Synthetic
Lead Time	In Stock
Notes	Research Use Only

Purity	≥ 95%
Form	Lyophilized powder
Storage	-20°C in a cool and dry place
Stability	≥ 2 years
Packaging	PP screw vials

Product Manual	Technical Specification MSDS

Reference	1. Pietrocola, F., Galluzzi, L., Bravo-San Pedro, J. M., Madeo, F., & Kroemer, G. (2015). Acetyl coenzyme A: A central metabolite and second messenger. Cell Metabolism, 21(6), 805-821. 2. Shi, L., & Tu, B. P. (2015). Acetyl-CoA and the regulation of metabolism: Mechanisms and consequences. Current Opinion in Cell Biology, 33, 125-131. 3. Sibon, O. C. M., & Strauss, E. (2016). Coenzyme A: To make it or uptake it? Nature Reviews Molecular Cell Biology, 17(10), 606-607. 4. Spry, C., Kirk, K., & Saliba, K. J. (2008). Coenzyme A biosynthesis: An antimicrobial drug target. FEMS Microbiology Reviews, 32(1), 56-106.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHB21200005-1	A-08-10MG	10mg	$147.73		Add to Cart
BHB21200005-2	A-08-25MG	25mg	$301.14		Add to Cart
BHB21200005-3	A-08-50MG	50mg	$511.36		Add to Cart
BHB21200005-4	A-08-100MG	100mg	$909.09		Add to Cart

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