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Compound Overview
Laulimalide (CAS 115268-43-4) is a research-grade small molecule supplied by TargetMol.
Physical Properties
| CAS Number | 115268-43-4 |
|---|---|
| Molecular Formula | C30H42O7 |
| Molecular Weight | 514.65 g/mol |
| SMILES | O(CH)1(C)2((C)(O2)(C(C)((CH)(/C=C/(CH)3CC(C)=CCO3)O)(OC(=O)/C=C/C(C)4(… |
| Form | Solid |
| Shipping | Room Temperature (RT) |
Biological Activity
Microtubule stabilizing agent. Potent inhibitor of cellular proliferation in cancer cell lines (IC50 reported to be 3-30 nM, dependent on cell line used). Causes cells to arrest in the prometaphase of the cell cycle, prevents formation of bipolar spindle and increases kinetochore tension in preformed spindles.
Safety & Regulatory
For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.
It is recommended to sonicate at a lower frequency
mg/mL (milligrams per milliliter) and mM (millimolar = millimoles per liter) are two concentration units for the same solution. To convert: mM = (mg/mL × 1000) / MW (g/mol). For example, for a compound with MW = 350 g/mol: 1 mg/mL = 1000/350 = 2.86 mM. Use the molar concentration calculator on the TargetMol website for quick conversions.
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- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
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- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
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