| Field | Specification |
|---|---|
| Activity | |
| Alternative Names | S-MGB-234 |
| Cas No. | |
| Molecular Weight | |
| Product Type | |
| Signaling Pathway | |
| SMILES | |
| Target |
Compound Overview
S-MGB-234 TFA (CAS 1970223-54-1) is a research-grade small molecule supplied by TargetMol.
Alternative names: S-MGB-234
Physical Properties
| CAS Number | 1970223-54-1 |
|---|---|
| Molecular Formula | C34H34F6N8O8 |
| Molecular Weight | 796.67 g/mol |
| SMILES | OC(C(F)(F)F)=O.O=C(C1=CC(NC(C2=CN=C(/C=C/C3=CC=C(C=C3)OC)C=C2)=O)=CN1C… |
| Form | Solid |
| Shipping | Room Temperature (RT) |
Biological Activity
S-MGB-234 is a novel Minor Groove Binder that cures animal African trypanosomiasis in an in vivo mouse model. S-MGB-234 has significant potential as novel therapeutic agents for animal African trypanosomiasis.
Safety & Regulatory
For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.
Try the following steps: (1) warm the DMSO solvent to 37–50 °C before adding the compound; (2) vortex vigorously for 30 seconds then bath-sonicate for 1–2 minutes; (3) if still undissolved, prepare a more dilute stock. Note that maximum solubility values are reference conditions — actual solubility can vary with temperature, solvent lot, and compound batch. Contact BioHippo support if dissolution problems persist.
Melted ice packs are generally not a concern for solid powder compounds, as the short transit period at ambient temperature does not typically affect compound integrity or potency. Powder form is inherently more stable than solution form during temperature fluctuations. Upon receipt, transfer the compound to −20 °C immediately. If you observe color change, odor, or physical changes, contact BioHippo for quality investigation.
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
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