| Field | Specification |
|---|---|
| Activity | |
| Alternative Names | 4',5,7-Trihydroxyisoflavone, 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, 4′,5,7-Trihydroxyisoflavone, 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
| Cas No. | |
| Form | Creamy off-white solid |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | Soluble in DMSO (30 mg/ml), 100% ethanol (4 mg/ml) or dilute aqueous base; insoluble in water |
| Source | Synthetic |
| Storage |
Genistein is a naturally occurring isoflavone with a broad range of biological activities. It functions as an inhibitor of tyrosine protein kinases, including EGFR kinase, and also inhibits DNA topoisomerase and α-glucosidase. In neuroscience, Genistein is studied for its neuroprotective, antioxidant, and anti-inflammatory properties. It induces cell cycle arrest and apoptosis, modulates insulin signaling, and inhibits endocytosis. These actions make Genistein a valuable compound for exploring neurodegenerative disease mechanisms involving oxidative stress, metabolic dysfunction, and aberrant kinase signaling.
Classification: Acute toxicity, Oral (Category 4), H302
Safety Phrases:
- S22 - Do not breathe dust.
- S24/25 - Avoid contact with skin and eyes.
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Hazard statements:
H302 Harmful if swallowed
Precautionary statements:
- P264 Wash skin thoroughly after handling.
- P270 Do not eat, drink or smoke when using this product.
- P301 + P312 IF SWALLOWED: Call a POISON CENTER or doctor/ physician if you feel unwell.
- P330 Rinse mouth.
- P501 Dispose of contents/ container to an approved waste disposal plant.
Genistein (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-446)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
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equivalents, or discuss custom synthesis with the right QC documentation (RUO).
2. Bazuine M., van den Broek P.J.A., & Maassen J. A. (2005) Biochem. Biophys. Res. Comm. 326(2): 511–514.
3. Linassier C., Pierre M., Le Pecq J.B., & Pierre J. (1990) Biochem. Pharm. 39(1): 187–193.
4. Dean N.M., Kanemitsu M., & Boynton A.L. (1989) Biochem. Biophys. Res. Comm. 165(2): 795–801.
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