| Field | Specification |
|---|---|
| Activity | |
| Alternative Names | 2-[Benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate hydrochloride (1:1) |
| Cas No. | |
| Form | Yellow solid |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | Soluble in DMSO (1 mg/ml), ethanol:water 25:75-70:30, propylene glycol, or methanol; slightly soluble in acetone, 100% ethanol, chloroform and water. |
| Source | Synthetic |
| Storage |
Nicardipine HCl is a dihydropyridine calcium channel blocker used to treat vascular disorders. In neuroscience, it is employed to investigate cerebral blood flow regulation and neurovascular coupling. Nicardipine’s inhibition of calcium influx in smooth muscle cells can influence cerebral perfusion and has been studied in models of stroke, traumatic brain injury, and migraine. Its role in modulating neurovascular responses makes it a valuable tool in neuropharmacology.
Classification: Toxic. May be harmful or fatal if inhaled, swallowed or absorbed through skin.
Safety Phrases:
- S22 - Do not breathe dust
- S24/25 - Avoid contact with skin and eyes
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
- S45- In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
Risk Phrases:
R23/24/25- Toxic by inhalation, if swallowed and in contact with skin.
Hazard Phrases:
H301-H311-H331
Precautionary Phrases:
P261-P280-P301 + P310-P311
Nicardipine HCl (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-313)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
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