| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | GPSM1; AGS3; G-protein-signaling modulator 1; Activator of G-protein signaling 3 |
| Clonality | |
| Concentration | |
| Formulation | |
| Gene ID | |
| Host | |
| Immunogen | Synthesized peptide derived from the Internal region of human AGS3. |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Product Overview
Primary AntibodyThis antibody targets GPSM1 and detects endogenous levels of GPSM1 protein.
Validated Applications
| Application | Dilution Guidance |
|---|---|
| Immunohistochemistry (IHC) | Refer to datasheet for recommended working dilution |
| ELISA | Refer to datasheet for recommended working dilution |
Antibody Specifications
| Target | GPSM1 |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Reactivity | Human, Mouse, Rat |
| Purification | Affinity Purification |
| Molecular Weight | ~72.1 kDa |
| Concentration | 1 mg/ml |
| Immunogen | Synthesized peptide derived from the Internal region of human AGS3. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Gene ID | Human: 26086; Mouse: 67839; Rat: 246254 |
| UniProt | Q86YR5 (Human: Q86YR5; Mouse: Q6IR34; Rat: Q9R080) |
Scientific Background
G-protein signaling modulators (GPSMs) play diverse functional roles through their interaction with G-protein subunits. GPSM1 encodes a receptor-independent activator of G protein signaling, which is one of several factors that influence the basal activity of G-protein signaling systems. The G-protein signaling modulator 1 contains seven tetratricopeptide repeats in its N-terminal half and four G-protein regulatory (GPR) motifs in its C-terminal half. Multiple alternatively spliced transcript variants encoding different isoforms have been found for GPSM1.
Alternative Names
GPSM1; AGS3; G-protein-signaling modulator 1; Activator of G-protein signaling 3
Safety & Handling
| Target | GPSM1 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Reactivity | Human, Mouse, Rat |
| Purification | Affinity Purification |
| Molecular Weight | ~72.1 kDa |
| Concentration | 1 mg/ml |
| Immunogen | Synthesized peptide derived from the Internal region of human AGS3. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage | -20°C for 1 year |
| Gene ID | Human: 26086; Mouse: 67839; Rat: 246254 |
| UniProt | Q86YR5 (Human: Q86YR5; Mouse: Q6IR34; Rat: Q9R080) |
Optimized working dilutions depend on sample type and detection system. Titration is recommended.
| Application | Dilution Note |
|---|---|
| Immunohistochemistry (IHC) | Refer to datasheet for recommended working dilution |
| ELISA | Refer to datasheet for recommended working dilution |
G-protein signaling modulators (GPSMs) play diverse functional roles through their interaction with G-protein subunits. GPSM1 encodes a receptor-independent activator of G protein signaling, which is one of several factors that influence the basal activity of G-protein signaling systems. The G-protein signaling modulator 1 contains seven tetratricopeptide repeats in its N-terminal half and four G-protein regulatory (GPR) motifs in its C-terminal half. Multiple alternatively spliced transcript variants encoding different isoforms have been found for GPSM1.
Alternative Names
GPSM1; AGS3; G-protein-signaling modulator 1; Activator of G-protein signaling 3
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
