| Field | Specification |
|---|---|
| Target | |
| Alternative names | Formimidoyltransferase-cyclodeaminase;Formiminotransferase-cyclodeaminase;FTCD;LCHC1;Glutamate formimidoyltransferase;2.1.2.5;Glutamate formiminotransferase;Glutamate formyltransferase;Formimidoyltetrahydrofolate cyclodeaminase;4.3.1.4;Formiminotetrahydrofolate cyclodeaminase;FTCD; |
| Gene ID | |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human 58K Golgi protein |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone AODH-6 is a rabbit monoclonal antibody that recognizes formimidoyltransferase-cyclodeaminase (gene FTCD) in human samples and is validated for Western blot, IHC and flow cytometry. The predicted molecular weight is 58.9 kDa, and the supplier reports an observed band at about 58 kDa.
Formimidoyltransferase-cyclodeaminase (FTCD) is a bifunctional folate-dependent enzyme in the histidine breakdown pathway, moving one-carbon units from formiminoglutamate into the folate pool. It is abundant in liver and is also known as the 58K Golgi protein, where it can bind and bundle vimentin filaments.
| Target | Formimidoyltransferase-cyclodeaminase (gene FTCD; UniProt O95954, human) |
|---|---|
| Clone | AODH-6 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / Rabbit IgG |
| Reactivity | Human |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 58.9 kDa |
| Observed MW | 58 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|---|
| Immunohistochemistry | 1:50–1:200 |
| Flow cytometry | 1:20 |
Samples with a confirmed band (WB): human fetal liver.
Recommended loading (WB): 20–40 µg of total protein per lane.
Immunogen
Synthetic peptide based on the sequence of human 58K Golgi protein.
Reactivity Notes
The supplier lists reactivity with human. UniProt places formimidoyltransferase-cyclodeaminase in the cytoplasm and Golgi apparatus. The samples tested by the supplier (listed above) are a practical starting point for positive controls.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
