| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Type-2 angiotensin II receptor;Angiotensin II type-2 receptor;AT2;AGTR2; |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Gene ID | |
| Host | |
| Immunogen | A synthesized peptide derived from human AGTR2 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Overview
Anti-AGTR2/Angiotensin Ii Type 2 Receptor Rabbit Monoclonal Antibody is an antibody targeting AGTR2. Common applications include WB, IP. Key specifications include host: Rabbit; clonality: Monoclonal; clone: Clone: FIO-1; isotype: Rabbit IgG; reactivity: Human,Mouse,Rat; observed MW: 45 kDa; calculated MW: 41184 MW.
Boster Bio Anti-AGTR2/Angiotensin Ii Type 2 Receptor Rabbit Monoclonal Antibody catalog # M00432. Tested in WB, IP applications. This antibody reacts with Human, Mouse, Rat.
Key elements and design rationale
- Target: AGTR2 — Type-2 angiotensin II receptor
- Antibody format: Host: Rabbit; Clonality: Monoclonal; Clone: Clone: FIO-1; Isotype: Rabbit IgG
- Species reactivity: Human,Mouse,Rat
- Molecular weight guidance: Observed: 45 kDa; Calculated: 41184 MW
Biological background
Protein function (datasheet): Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation. .
Cellular localization (datasheet): Cell membrane; Multi-pass membrane protein.
Tissue details (datasheet): In adult, highly expressed in myometrium with lower levels in adrenal gland and fallopian tube. Expressed in the cerebellum. Very highly expressed in fetal kidney and intestine. .
Research relevance and current trends
- Commonly studied in contexts related to Apoptosis,Atherosclerosis,Cardiovascular,G Protein Signaling,Lipid Signaling,Signal Transduction,Signaling Pathway.
- Supports comparative expression analysis across conditions, genotypes, or treatments when paired with appropriate controls.
- Useful for confirming target presence and subcellular distribution using orthogonal readouts (e.g., microscopy vs. immunoblotting).
Common research applications
- Western blot (WB): Compare relative target abundance and apparent size/isoforms across samples; interpret bands in light of expected MW and potential PTMs.
Notes for experimental interpretation
- Consider isoforms, post-translational modifications, and processing that can shift apparent molecular weight or localization.
- Use appropriate positive and negative controls (e.g., KO/KD, blocking peptide, or isotype controls) to support specificity interpretation.
As a monoclonal antibody, this reagent is expected to recognize a defined epitope, which can support consistency across lots when epitope accessibility is preserved.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
