Anti-ARG1/Arginase 1 Rabbit Monoclonal Antibody

Overview

Anti-ARG1/Arginase 1 Rabbit Monoclonal Antibody is an antibody targeting ARG1. Common applications include WB, IP. Key specifications include host: Rabbit; clonality: Monoclonal; clone: Clone: ADG-1; isotype: Rabbit IgG; reactivity: Human,Mouse,Rat; observed MW: 36, 38 kDa; calculated MW: 34735 MW.

Boster Bio Anti-ARG1/Arginase 1 Rabbit Monoclonal Antibody catalog # M01106-1. Tested in WB, IP applications. This antibody reacts with Human, Mouse, Rat.

Key elements and design rationale

• Target: ARG1 — Arginase-1
• Antibody format: Host: Rabbit; Clonality: Monoclonal; Clone: Clone: ADG-1; Isotype: Rabbit IgG
• Species reactivity: Human,Mouse,Rat
• Molecular weight guidance: Observed: 36, 38 kDa; Calculated: 34735 MW

Biological background

Protein function (datasheet): Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes. .

Cellular localization (datasheet): Cytoplasm .

Tissue details (datasheet): Isoform 1 and isoform 2 were identified in platelets and megakaryocytes, but not in reticulocytes or in Jurkat and U-937 white blood cell line. Isoform 3 is expressed by leukemia, prostate adenocarcinoma and melanoma cells but not by platelets or normal prostate or breast epithelial cells.

Research relevance and current trends

• Commonly studied in contexts related to Biochemicals,Chemical Type,Neurology Process,Neuroscience.
• Supports comparative expression analysis across conditions, genotypes, or treatments when paired with appropriate controls.
• Useful for confirming target presence and subcellular distribution using orthogonal readouts (e.g., microscopy vs. immunoblotting).

Common research applications

• Western blot (WB): Compare relative target abundance and apparent size/isoforms across samples; interpret bands in light of expected MW and potential PTMs.

Notes for experimental interpretation

• Consider isoforms, post-translational modifications, and processing that can shift apparent molecular weight or localization.
• Use appropriate positive and negative controls (e.g., KO/KD, blocking peptide, or isotype controls) to support specificity interpretation.

As a monoclonal antibody, this reagent is expected to recognize a defined epitope, which can support consistency across lots when epitope accessibility is preserved.

Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.