| Field | Specification |
|---|---|
| Target | |
| Alternative names | C-X-C chemokine receptor type 6;CXC-R6;CXCR-6;CDw186;G-protein coupled receptor STRL33;G-protein coupled receptor bonzo;CD186;CXCR6;BONZO, STRL33, TYMSTR; |
| Gene ID | |
| UniProt # | |
| Host | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human Bonzo, different from the related mouse and rat sequences by three amino acids. |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
This rabbit polyclonal antibody recognizes C-X-C chemokine receptor type 6 (gene CXCR6) in human samples and is validated for Western blot and IHC. The predicted molecular weight is 39.3 kDa, and the supplier reports an observed band at about 39 kDa.
CXCR6 is a G protein-coupled receptor for the chemokine CXCL16. It is expressed on subsets of T cells, NKT cells and innate lymphoid cells and helps position them in tissues such as the liver. CXCR6 also serves as a coreceptor for SIV and some HIV strains, and it is studied in tissue-resident immunity.
| Target | C-X-C chemokine receptor type 6 (gene CXCR6; UniProt O00574, human) |
|---|---|
| Host / Clonality / Isotype | Rabbit / Polyclonal / Rabbit IgG |
| Reactivity | Human |
| Form | Lyophilized |
| Formulation | Per vial: 4 mg trehalose; 0.9 mg NaCl; 0.2 mg Na2HPO4; 0.05 mg NaN3 |
| Calculated MW | 39.3 kDa |
| Observed MW | 39 kDa |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| IHC (paraffin sections) | 0.5–1 µg/mL (Human) |
|---|---|
| Western blot | 0.1–0.5 µg/mL (Human) |
Samples with a confirmed band (WB): HeLa cells, Jurkat cells, MCF-7 cells.
Recommended loading (WB): 20–40 µg of total protein per lane.
Samples with confirmed staining (IHC): human tonsil tissue.
Recommended antigen retrieval: heat-mediated, in TE buffer (pH 9.0); citrate buffer (pH 6.0) can be used instead.
Immunogen
Synthetic peptide from the C-terminal region of human bonzo. It differs from the mouse and rat sequences at three residues.
Reactivity Notes
The supplier lists reactivity with human. UniProt places C-X-C chemokine receptor type 6 in the cell membrane. Tissue expression noted by UniProt (human): Expressed in lymphoid tissues and activated T cells. The samples tested by the supplier (listed above) are a practical starting point for positive controls.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
