| Field | Specification |
|---|---|
| Target | |
| Alternative names | Caveolin-2;CAV2; |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human Caveolin-2 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone FD-3 is a rabbit monoclonal antibody that recognizes caveolin-2 (gene CAV2) in human samples and is validated for Western blot, IHC, ICC/IF and immunoprecipitation. The predicted molecular weight is 18.3 kDa, and the supplier reports an observed band at about 18 kDa.
Caveolin-2 (CAV2) is a caveolar membrane protein that forms hetero-oligomers with caveolin-1 and depends on it for proper localization. It contributes to caveolae formation and has been linked to regulation of signaling, including through its phosphorylated forms. It is often studied alongside caveolin-1 in adipocytes, endothelium and lung.
| Target | Caveolin-2 (gene CAV2; UniProt P51636, human) |
|---|---|
| Clone | FD-3 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / Rabbit IgG |
| Reactivity | Human |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 18.3 kDa |
| Observed MW | 18 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|---|
| Immunohistochemistry | 1:50–1:200 |
| Immunocytochemistry / Immunofluorescence | 1:50–1:200 |
| Immunoprecipitation | 1:20 |
Samples with confirmed staining (IHC): human colon tissue.
Recommended antigen retrieval: heat-mediated, in TE buffer (pH 9.0); citrate buffer (pH 6.0) can be used instead.
Immunogen
Synthetic peptide based on the sequence of human caveolin-2.
Reactivity Notes
The supplier lists reactivity with human. UniProt places caveolin-2 in the nucleus, cytoplasm, Golgi apparatus membrane and cell membrane. Tissue expression noted by UniProt (human): Expressed in endothelial cells, smooth muscle cells, skeletal myoblasts and fibroblasts. The samples tested by the supplier (listed above) are a practical starting point for positive controls.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
