| Field | Specification |
|---|---|
| Mfr No | |
| Clonality | |
| Concentration | |
| Formulation | |
| Immunogen | Human erythroleukemia cell line OCIM1 |
| Isotype | |
| Product Type | |
| Purity | |
| Reactivity | |
| Shipping | |
| Storage |
Product Overview
Anti-CD117 Antibody recognizes human CD117.
Encoded by the KIT gene, the CD117 antigen is also known as c-Kit and stem cell factor receptor (SCFR). The CD117 antigen is expressed primarily on hematopoietic progenitor cells, mast cells and neural crest-derived melanocytes. CD117 is a type I transmembrane glycoprotein in the receptor tyrosine kinase (RTK) family which functions in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenensis, mast cell development, migration and function, and in melanogenesis. Mutations with the KIT gene are associated with diseases such as gastrointestinal stromal tumor and piebaldism.
Validated Applications
| Application | Recommended Dilution |
|---|---|
| Flow cyt | See datasheet |
Product Specifications
| Clonality | Monoclonal |
|---|---|
| Host Species | Mouse |
| Isotype | IgG2 |
| Species Reactivity | Human |
| Purification | The antibody was affinity-purified from hybridoma supernatant by affinity-chromatography. |
| Concentration | 100ug/100ul |
| Formulation | Liquid |
| Storage | This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
Immunogen / Antigen
Human erythroleukemia cell line OCIM1
Safety & Handling
For Research Use Only (RUO). Not for diagnostic or therapeutic use. Handle as a potential biohazard in accordance with good laboratory practices.
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This antibody has been validated for Flow cyt. Always refer to the product datasheet for recommended dilution ranges and appropriate positive control samples for each application type.
Validated reactivity has been confirmed for Human. Cross-reactivity with additional species may exist based on sequence homology but has not been confirmed by the manufacturer. For unlisted species, we recommend running a preliminary validation experiment.
This antibody was raised in Mouse. For indirect detection (WB, IHC, IF), select an anti-Mouse secondary antibody that matches the isotype. For direct detection, check the variant selector for conjugated formats. Confirm secondary antibody compatibility before ordering.
Human erythroleukemia cell line OCIM1
Please refer to the storage conditions on the product label and datasheet. As a general best practice: upon receipt, aliquot into single-use volumes to minimize freeze-thaw cycling, which can progressively reduce antibody performance and lead to aggregation.
Validated reactivity covers Human samples. Performance can vary across different cell lines and tissue types depending on target antigen expression levels and epitope accessibility. We recommend verifying target expression in your specific model system using a known positive control before proceeding to experimental samples.
BioHippo offers customization and value-added services for qualified research programs:
- Bulk Pricing: Volume discounts available for orders of 5 or more units. Request a quote through the Contact Us page.
- Custom Conjugation: Select antibody products are available for custom conjugation to fluorophores, biotin, HRP, or other detection labels upon request. Minimum quantities apply.
- Custom Formats: Lyophilized or concentrated formats may be available for select products. Inquire before ordering.
- Technical Support: Our scientific team is available to assist with application optimization, protocol troubleshooting, and experimental design.
For customization inquiries, please use the Contact Us page or reach out to our support team directly.
