| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1;3.2.2.6;2'-phospho-ADP-ribosyl cyclase;2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase;2.4.99.20;2'-phospho-cyclic-ADP-ribose transferase;ADP-ribosyl cyclase 1;ADPRC 1;Cyclic ADP-ribose hydrolase 1;cADPr hydrolase 1;T10;CD38;CD38; |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Host | |
| Immunogen | A synthesized peptide derived from human CD38 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Overview
Anti-CD38 Rabbit Monoclonal Antibody is an antibody targeting CD38. Common applications include WB, IHC. Key specifications include host: Rabbit; clonality: Monoclonal; clone: Clone: GAD-3; isotype: Rabbit IgG; reactivity: Human; observed MW: 45 kDa; calculated MW: 34328 MW.
Boster Bio Anti-CD38 Rabbit Monoclonal Antibody catalog # M00193. Tested in WB, IHC applications. This antibody reacts with Human.
Key elements and design rationale
- Target: CD38 — ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
- Antibody format: Host: Rabbit; Clonality: Monoclonal; Clone: Clone: GAD-3; Isotype: Rabbit IgG
- Species reactivity: Human
- Molecular weight guidance: Observed: 45 kDa; Calculated: 34328 MW
Biological background
Protein function (datasheet): Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.
Cellular localization (datasheet): Membrane; Single-pass type II membrane protein.
Tissue details (datasheet): Expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. .
Research relevance and current trends
- Commonly studied in contexts related to Adaptive Immunity,B Cells,Cancer,Cancer Metabolism,Hematopoietic Progenitors,Immunology,Lymphoid,Metabolism,Metabolism Processes,Myeloid,Pathways and Processes,Response To Hypoxia,Stem Cells,Surface Molecules,T Lymphocytic Lineage.
- Supports comparative expression analysis across conditions, genotypes, or treatments when paired with appropriate controls.
- Useful for confirming target presence and subcellular distribution using orthogonal readouts (e.g., microscopy vs. immunoblotting).
Common research applications
- Western blot (WB): Compare relative target abundance and apparent size/isoforms across samples; interpret bands in light of expected MW and potential PTMs.
- Immunohistochemistry (IHC): Assess tissue distribution and cell-type patterns; interpret staining with appropriate negative controls and antigen context.
Notes for experimental interpretation
- Consider isoforms, post-translational modifications, and processing that can shift apparent molecular weight or localization.
- Use appropriate positive and negative controls (e.g., KO/KD, blocking peptide, or isotype controls) to support specificity interpretation.
As a monoclonal antibody, this reagent is expected to recognize a defined epitope, which can support consistency across lots when epitope accessibility is preserved.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
