| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Thy-1 membrane glycoprotein;CDw90;Thy-1 antigen;CD90;THY1; |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Form | Liquid |
| Host | |
| Immunogen | A synthesized peptide derived from human CD90 / Thy1 |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Storage | |
| Target | |
| UniProt # |
Overview
This product is an anti-THY1 antibody for target detection and characterization. Key identifiers include host species: Rabbit; Monoclonal; clone CEB-20; isotype Rabbit IgG; reactivity: Human,Rat. Reported application contexts include WB, IHC (as provided in the source record). Boster Bio Anti-CD90 / Thy1 Rabbit Monoclonal Antibody catalog # M01818. Tested in WB, IHC applications. This antibody reacts with Human, Rat.
Key elements and design rationale
- Target: THY1 (Thy-1 membrane glycoprotein).
- Antibody format: Monoclonal; clone CEB-20; isotype Rabbit IgG.
- Host: Rabbit.
- Species reactivity: Human,Rat (confirm in your model system with appropriate controls).
This description is intended to help interpret the antibody design and the biological context of the target using the fields provided in the catalog record, alongside general experimental considerations.
Biological background
THY1 (protein: Lysosome-associated membrane glycoprotein 2 (Lamp2)) is a commonly studied target in molecular and cellular biology. Functional context (as provided): May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. Reported cellular localization context: Cell membrane ; Lipid-anchor, GPI-anchor . Tissue expression notes (as provided): Detected adjacent to nodes of Ranvier in juxtaparanodal zones in spinal cord nerve fibers, but also in paranodal regions in some myelinated spinal cord axons (at protein level) (PubMed:11086297). Detected in the islet of Langerhans (PubMed:21483673). .
Research relevance and current trends
- Research context keywords from the source record include: Adaptive Immunity,Cell Type Marker,Hematopoietic Progenitors,Immunology,Lymphoid,Myeloid,Neuron Marker,Neuroscience,Stem Cells,Synapse Marker,T Cells,T Lymphocytic Lineage.
- Current studies often focus on connecting target abundance/localization to pathway perturbations across models, tissues, and cell states.
- Quantitative and multiplexed assays (e.g., imaging + immunoblot panels) are commonly used to compare phenotypes across conditions and time-courses.
Common research applications
- Western blotting (WB): assess relative target abundance across samples, treatments, or time-points.
- Immunohistochemistry (IHC): evaluate spatial distribution of target-positive staining in tissue architecture.
Workflow ideas (metafield): Validate THY1 antibody specificity using KO/KD control samples (WB/IF/IHC as appropriate), Detect THY1 expression by Western blot in cell or tissue lysates, Detect THY1 in FFPE tissue sections by immunohistochemistry
Notes for experimental interpretation
- Consider isoforms and post-translational modifications (PTMs) that may shift apparent molecular weight or epitope accessibility.
- Apparent molecular weight may vary by sample type and processing (observed MW: 18 kDa; calculated MW: 17935 MW).
- Control concepts: include appropriate negative controls (e.g., isotype, KO/KD samples) and orthogonal validation when feasible.
Additional product details (from the source record)
- Molecular weight (observed): 18 kDa
- Cellular localization (provided): Cell membrane ; Lipid-anchor, GPI-anchor .
- Tissue details (provided): Detected adjacent to nodes of Ranvier in juxtaparanodal zones in spinal cord nerve fibers, but also in paranodal regions in some myelinated spinal cord axons (at protein level) (PubMed:11086297). Detected in the islet of Langerhans (PubMed:21483673). .
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
