| Field | Specification |
|---|---|
| Target | |
| Alternative names | Protein Cdc25c ;Cdc25c ; |
| Gene ID | |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | Recombinant human Cdc25c. |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone DCS-193 is a mouse monoclonal antibody that recognizes M-phase inducer phosphatase (gene Cdc25c) in human samples and is validated for Western blot.
CDC25C is a dual-specificity phosphatase that activates the CDK1–cyclin B complex by removing inhibitory phosphates, triggering entry into mitosis. It is held inactive by checkpoint kinases after DNA damage, which makes it a key node linking the G2/M checkpoint to cell cycle progression.
| Target | M-phase inducer phosphatase (gene Cdc25c; UniProt D4ADT2, rat) |
|---|---|
| Clone | DCS-193 |
| Host / Clonality / Isotype | Mouse / Monoclonal / Mouse IgG1 |
| Reactivity | Human |
| Purification | Ascites |
| Form | Lyophilized |
| Formulation | 1.2% sodium acetate; 0.01 mg NaN3; plus stabilizers |
| Reconstitution | 100 µg/mL after adding 1 mL PBS |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1–2 µg/mL (Human) |
|---|
Immunogen
Recombinant human Cdc25c.
Reactivity Notes
The supplier lists reactivity with human.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
Ping Lin et al. (2018) Prostate cancer cell proliferation is suppressed by microRNA‑3160‑5p via targeting of F‑box and WD repeat domain containing 8. Oncology Letters. 10.3892/ol.2018.8505
