| Field | Specification |
|---|---|
| Target | |
| Alternative names | Cyclin-dependent kinase 7;2.7.11.22;2.7.11.23;39 protein kinase;P39 Mo15;CDK-activating kinase 1;Cell division protein kinase 7;TFIIH basal transcription factor complex kinase subunit;Cdk7;Cak, Cak1, Mo15; |
| Gene ID | |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | Recombinant human Cdk7 protein. |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Lyophilized |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone MO-1.1 is a mouse monoclonal antibody that recognizes cyclin-dependent kinase 7 (gene Cdk7) in human samples and is validated for Western blot, IHC and ICC/IF.
CDK7 is the kinase at the core of the CDK-activating kinase (CAK), which it forms with cyclin H and MAT1. It activates other CDKs such as CDK1 and CDK2 by phosphorylating their T-loop, and as part of the general transcription factor TFIIH it phosphorylates RNA polymerase II, linking cell cycle control to transcription.
| Target | Cyclin-dependent kinase 7 (gene Cdk7; UniProt P51952, rat) |
|---|---|
| Clone | MO-1.1 |
| Host / Clonality / Isotype | Mouse / Monoclonal / Mouse IgG2b |
| Reactivity | Human |
| Purification | Ascites |
| Form | Lyophilized |
| Formulation | 1.2% sodium acetate; 0.01 mg NaN3; plus stabilizers |
| Reconstitution | 100 µg/mL after adding 1 mL PBS |
| Storage | As supplied: −20 °C for up to 12 months from receipt. After reconstitution: 4 °C for up to 1 month, or aliquot and keep at −20 °C for up to 6 months. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 0.25 µg/mL (Human) |
|---|---|
| Immunohistochemistry | Not specified by the supplier |
| Immunocytochemistry / Immunofluorescence | Not specified by the supplier |
Immunogen
Recombinant human Cdk7 protein.
Reactivity Notes
The supplier lists reactivity with human. UniProt places cyclin-dependent kinase 7 in the nucleus and cytoplasm.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
