| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | CEMIP2; KIAA1412; TMEM2; Cell surface hyaluronidase; EC 3.2.1.35; Cell migration-inducing hyaluronidase 2; Transmembrane protein 2 |
| Clonality | |
| Concentration | |
| Host | |
| Immunogen | E.coli-derived human CEMIP2 recombinant protein (Position: E55-R1225). Human CEMIP2 shares 89% amino acid (aa) sequence identity with mouse CEMIP2. |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Boster Bio Anti-CEMIP2 Antibody Picoband® catalog # A31759-1. Tested in WB, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Scientific background: This gene encodes a type II transmembrane protein that belongs to the interferon-induced transmembrane (IFITM) protein superfamily. The encoded protein functions as a cell surface hyaluronidase that cleaves extracellular high molecular weight hyaluronan into intermediate size fragments before internalization and degradation in the lysosome. It also has an interferon-mediated antiviral function in humans through activation of the JAK STAT signaling pathway. The activation of this gene by transcription factor SOX4 in breast cancer cells has been shown to mediate the pathological effects of SOX4 on cancer progression. Naturally occurring mutations in this gene are associated with autosomal recessive non-syndromic hearing loss.
Cross reactivity: No cross-reactivity with other proteins
Protein: Cell surface hyaluronidase CEMIP2 | Gene: cell migration inducing hyaluronidase 2 | Target: CEMIP2
Host: Rabbit | Clonality/Clone: Polyclonal | Isotype: Rabbit IgG | Reactivity: Human | Immunogen: E.coli-derived human CEMIP2 recombinant protein (Position: E55-R1225). Human CEMIP2 shares 89% amino acid (aa) sequence identity with mouse CEMIP2. | Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml. | Purification: Immunogen affinity purified.
Applications: WB, IHC, ICC, ELISA
Observed MW: 147 kDa | Calculated MW: 147 kDa
Status: Active
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