| Field | Specification |
|---|---|
| Target | |
| Alternative names | Visual system homeobox 2; Ceh-10 homeodomain-containing homolog; Homeobox protein CHX10; VSX2; CHX10; HOX10 |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human CHX10 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone 24V98 is a rabbit monoclonal antibody that recognizes visual system homeobox 2 (gene VSX2) in human, mouse and rat samples and is validated for Western blot and flow cytometry. The predicted molecular weight is 39.4 kDa, and the supplier reports an observed band at about 50 kDa.
VSX2 (CHX10) is a homeodomain transcription factor that is essential for development of the neural retina. It is expressed in retinal progenitor cells and later in bipolar cells, and its loss causes microphthalmia. VSX2 also marks V2a interneurons in the spinal cord and is studied in eye and neural development.
| Target | Visual system homeobox 2 (gene VSX2; UniProt P58304, human) |
|---|---|
| Clone | 24V98 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / IgG |
| Reactivity | Human, Mouse, Rat |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 39.4 kDa |
| Observed MW | 50 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|---|
| Flow cytometry | 1:200 |
Immunogen
Synthetic peptide based on the sequence of human CHX10.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt places visual system homeobox 2 in the nucleus. Tissue expression noted by UniProt (human): Abundantly expressed in retinal neuroblasts during eye development and in the inner nuclear layer of the adult retina.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
Qi-You Li et al. (2025) Inhibition of IGF-1Rα affects the differentiation fate of rat optic cup-derived retinal stem cells to retinal ganglion cells in vitro. International Journal of Ophthalmology. 10.18240/ijo.2025.04.03
