| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | High affinity immunoglobulin gamma Fc receptor I; IgG Fc receptor I; Fc-gamma RI; FcRI; Fc-gamma RIA; FcgammaRIa; CD64; FCGR1A; FCG1; FCGR1; IGFR1 |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Host | |
| Immunogen | E. coli-derived human FCGR1A recombinant protein (Position: Q16-H292). |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Reconstitution | |
| Target | |
| UniProt # |
Overview
This antibody is intended for detection of FCGR1A (BAG family molecular chaperone regulator 1) in biological samples using common immunoassay formats. It is typically selected based on target identity, species reactivity, clonality/clone information, and detection modality.
Vendor notes: Boster Bio Anti-FCGR1A Antibody Picoband® catalog # A02428-1. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Key elements and design rationale
- Antibody format: Rabbit Polyclonal Rabbit IgG
- Immunogen / epitope context: E. coli-derived human FCGR1A recombinant protein (Position: Q16-H292). (reported region: Q16-H292).
- Molecular weight context: reported MW: 70 kDa; calculated MW: 38779 MW
- Reactivity: Human,Rat
- Applications: ELISA, Flow Cytometry, WB
As a polyclonal antibody, the reagent recognizes multiple epitopes on the target, which can improve detection robustness but may increase sensitivity to sample-dependent epitope changes.
Biological background
BAG family molecular chaperone regulator 1; Fc fragment of IgG receptor Ia. High affinity immunoglobulin gamma Fc receptor I is a protein that in humans is encoded by the FCGR1A gene. It is mapped to 1q21.2. This gene encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1. Functional note: High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses. Reported localization: Cell membrane. Expression/tissue context: Monocyte/macrophage specific.
Research relevance and current trends
- Immunoglobulins: Researchers commonly examine how FCGR1A (BAG family molecular chaperone regulator 1) relates to this theme using model systems and orthogonal readouts.
- Immunology: Researchers commonly examine how FCGR1A (BAG family molecular chaperone regulator 1) relates to this theme using model systems and orthogonal readouts.
- Innate Immunity: Researchers commonly examine how FCGR1A (BAG family molecular chaperone regulator 1) relates to this theme using model systems and orthogonal readouts.
Common research applications
- Western blotting: compare relative FCGR1A (BAG family molecular chaperone regulator 1) levels across conditions; band patterns may reflect isoforms and processing.
- Flow cytometry: quantify target-positive populations and shifts in expression; gating strategy and background staining controls are essential.
- ELISA-compatible use: when applicable, interpret signal as relative abundance across sample sets with consistent handling and dilution strategy.
Notes for experimental interpretation
- Specificity notes: No cross reactivity with other proteins.
- Cross-reactivity: No cross-reactivity with other proteins.
- Isoforms and PTMs: Apparent size and signal patterns can differ across splice isoforms, proteolytic processing, and post-translational modifications.
- Controls: Include an isotype control (as relevant), no-primary control for imaging, and orthogonal validation such as KD/KO samples when available.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
