| Field | Specification |
|---|---|
| Target | |
| Alternative names | Fibroblast growth factor 1; FGF-1; Acidic fibroblast growth factor; aFGF; Endothelial cell growth factor; ECGF; Heparin-binding growth factor 1; HBGF-1; FGF1; FGFA |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human FGF1 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone 18F58 is a rabbit monoclonal antibody that recognizes fibroblast growth factor 1 (gene FGF1) in human, mouse and rat samples and is validated for Western blot and IHC. The predicted molecular weight is 17.5 kDa, and the supplier reports an observed band at about 17 kDa.
Fibroblast growth factor 1 (FGF1, acidic FGF) is a heparin-binding growth factor that activates all FGF receptors. It lacks a classical signal peptide but acts as a potent mitogen, and it regulates cell proliferation, survival, migration, differentiation and angiogenesis. FGF1 is studied in tissue repair, development and metabolic regulation.
| Target | Fibroblast growth factor 1 (gene FGF1; UniProt P05230, human) |
|---|---|
| Clone | 18F58 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / IgG |
| Reactivity | Human, Mouse, Rat |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 17.5 kDa |
| Observed MW | 17 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|---|
| Immunohistochemistry | 1:50–1:200 |
Immunogen
Synthetic peptide based on the sequence of human FGF1.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt describes fibroblast growth factor 1 as secreted and also located in the cytoplasm and nucleus. Tissue expression noted by UniProt (human): Predominantly expressed in kidney and brain.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
Zou Yuchi et al. (2020) Non-Mitogenic Fibroblast Growth Factor 1 Enhanced Angiogenesis Following Ischemic Stroke by Regulating the Sphingosine-1-Phosphate 1 Pathway. Frontiers in Pharmacology. 10.3389/fphar.2020.00059
Hui Meng et al. (2008) The effect of a self-assembling peptide nanofiber scaffold (peptide) when used as a wound dressing for the treatment of deep second degree burns in rats. Journal of Biomedical Materials Research Part B-Applied Biomaterials. 10.1002/jbm.b.31226
