| Field | Specification |
|---|---|
| Target | |
| Alternative names | Fibroblast growth factor receptor 2;FGFR-2;2.7.10.1;K-sam;KGFR;Keratinocyte growth factor receptor;CD332;FGFR2;BEK, KGFR, KSAM; |
| UniProt # | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | A synthesized peptide derived from human FGFR2 |
| Molecular weight | |
| Purification | |
| Reconstitution | |
| Cellular localization | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
Clone AAAD-6 is a rabbit monoclonal antibody that recognizes fibroblast growth factor receptor 2 (gene FGFR2) in human, mouse and rat samples and is validated for Western blot and immunoprecipitation. The predicted molecular weight is 92.0 kDa, and the supplier reports an observed band at about 145 kDa.
Fibroblast growth factor receptor 2 (FGFR2) is a receptor tyrosine kinase for FGFs that regulates cell proliferation, differentiation, migration and survival. Alternative splicing produces epithelial (IIIb) and mesenchymal (IIIc) forms with different ligand preferences. FGFR2 is important in limb, skull and organ development and is studied in craniosynostosis syndromes and cancer.
| Target | Fibroblast growth factor receptor 2 (gene FGFR2; UniProt P21802, human) |
|---|---|
| Clone | AAAD-6 |
| Host / Clonality / Isotype | Rabbit / Monoclonal / Rabbit IgG |
| Reactivity | Human, Mouse, Rat |
| Form | Liquid |
| Formulation | PBS (pH 7.4); 150 mM NaCl; 0.02% sodium azide; 50% glycerol; plus stabilizers |
| Calculated MW | 92.0 kDa |
| Observed MW | 145 kDa |
| Storage | Long term: −20 °C for up to 12 months. Frequent use: 4 °C for up to 1 month. Avoid repeated freeze–thaw cycles. |
Validated Applications
| Western blot | 1:500–1:2000 |
|---|---|
| Immunoprecipitation | 1:20 |
Immunogen
Synthetic peptide based on the sequence of human FGFR2.
Reactivity Notes
The supplier lists reactivity with human, mouse and rat. UniProt places fibroblast growth factor receptor 2 in the cell membrane, Golgi apparatus and cytoplasmic vesicle.
Safety
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
Xi-Feng Fu et al. (2021) MicroRNA‑203‑3p inhibits the proliferation, invasion and migration of pancreatic cancer cells by downregulating fibroblast growth factor 2. Oncology Letters. 10.3892/ol.2021.12887
